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previously published mouse data; Pubmed IDS: 12754511, 12839964 Experiment Overall Design: see Black, EP, et.al., Cancer Res. 2003 Jul 1;63(13):3716-23 and Huang, E., et.al. Nat Genet. 2003 Jun;34(2):226-30.
ORGANISM(S): Mus musculus 
Effector cytotoxic T lymphocytes (CTLs) are critical for ridding the body of infected or cancerous cells. Recognition of an antigenic ligand by the CTL’s T cell receptor (TCR) triggers a signalling cascade that ultimately results in the targeted release of cytolytic granules and/or secretion of cyto...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-16 | PXD034920 | Pride
These data show that the genes that distinguish myofibroblasts from fibroblasts are myriad, and that some genes not traditionally associated with myofibroblast differentiation may serve as novel therapeutic targets for fibrosing disorders. Gene expression levels were assessed from total RNA on the A...
ORGANISM(S): Homo sapiens 
It was demonstrated that mice with eIF4E that cannot be activated by phosphorylation (S209A) produced extracellular matrix (ECM) less conducive to breast cancer tumor invasion and metastasis. To examine whether this could in part bedue to differences in the protein composition we analyzed the proteo...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD028953 | Pride
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