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Beginning with precursor lesions, aberrant DNA methylation marks the entire spectrum of prostate cancer progression. We mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=2) from fifty nanograms of genomic DNA using Methylplex-Next Generation Sequencing (M-NGS). A...
ORGANISM(S): Homo sapiens 
RNAP II is frequently paused near gene promoters in mammals and its transition to productive elongation requires active recruitment of P-TEFb, a cyclin-dependent kinase for RNAP II and other key transcription elongation factors. A fraction of P-TEFb is sequestered in an inhibitory complex containing...
ORGANISM(S): Mus musculus 
Aim: To assess the gene expression profiles of peripheral blood mononuclear cells obtained from palindromic rheumatism patients during flares and between flares. Samples were paired so we could assess the differences in gene expression profiles per a given patient during a flare and between flares. ...
ORGANISM(S): Homo sapiens 
Molecular basis of flowering under natural long-day conditions in Arabidopsis
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-09-25 | PXD010518 | Pride
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