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UnknownComparative performance of large language models for patient-initiated ophthalmology consultations.
Not available
S-EPMC12497754 | biostudies-literature
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
ProteomicsProteotypic differences of follicular-patterned thyroid neoplasms
The diagnosis of follicular-patterned thyroid tumors such as follicular adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by prote...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036553 |
ProteomicsExtracellular Vesicle Biomarkers for Complement System Dysfunction in Schizophrenia
Schizophrenia has a high rate of misdiagnosis, leading to inappropriate or delayed treatment. Combining with extracellular vesicles’ (EVs) proteome profiling and XGBoost-based machine learning, we developed new pan-EVs markers and yielded personalized discrimination scores (PDS) for schizophrenia di...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040261 |
ProteomicsThermostable neurotoxins in processed scorpion medicinal material underlie its pharmaceutical basis in traditional Chinese medicine
Our work describes the first "map" of functionally active scorpion toxins in processed scorpion medicinal material and provides valuable information for unveiling the pharmaceutical basis for the “combat poison with poison to cure diseases” strategy in traditional Chinese medicine.
ORGANISM(S): Mesobuthus Martensii 
PXD012392 |
ProteomicsSIRT5-Mediated FDX1 Desuccinylation Confers Cuproptosis Resistance in Lung cancer
Cuproptosis, a copper-dependent cell death process induced by excessive copper, represents an emerging therapeutic strategy in oncology. However, tumor specific molecular pathways regulating this process remain poorly defined. Here, we demonstrate that copper levels are elevated in lung adenocarcino...
ORGANISM(S): Homo Sapiens 
PXD077292 |
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