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ProteomicsThe changes of Proteomeand Protein Phosphorylation reveals the protective roles of exogenous nitrogen in alleviating cadmium toxicityin poplar plants
Phytoremediation soil polluted by heavy metal has been drawn on a worldwide attention from human society. However, how to improve the efficiency of plant remediation of soil contaminated by cadmium remains unknown. Previous studies showed that nitrogen (N) significantly enhanced cadmium uptake in po...
ORGANISM(S): Populus yunnanensis 
2020-05-26 | PXD013360 | Pride
Plants Exogenous nitrogen Phosphorylation 
ProteomicsGlobal Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice
Phosphorylation is well-known in regulating various biological processes. However, comprehensively phosphoproteomic profiling in the termination of liver regeneration (LR) is still missing. Here, we used TMT labeling coupled with phosphopeptides enrichment and 2D LC-MS/MS analysis to establish a glo...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-04 | PXD011374 | Pride
Phosphorylation  partial hepatectomy  liver regeneration  metabolic reprogramming 
TranscriptomicsExpression profiling of breast cancer cell lines MCF-7 and MCF-7R4
Human breast cancer cell line MCF-7 is usually sensitive to chemotherapy drug BMS-554417, an insulin receptor (IR) and insulin-like growth factor receptor (IGFR) inhibitor. However, through step-wise increase in BMS-554417 doses in culture media, we were able able to screen and select a single MCF-7...
ORGANISM(S): Homo sapiens 
2009-11-05 | E-GEOD-18912 | biostudies-arrayexpress
Proteomics4D label free proteomics of membrane vesicles of RN4220 and the mutants RN4220-ΔHld and RN4220-ΔagrA
The 4D label free proteomics of membrane vedsicles (MVs) of Staphylococcus aureus RN4220 and the mutants RN4220-ΔHld, which the 20th base “C” in the hld gene was changed to “G” to achieve a stop codon TGA and result in a truncated translation of Hld, and RN4220-ΔagrA, which agrA gene was deleted.
ORGANISM(S): Staphylococcus Aureus 
2023-01-29 | PXD039734 |
ProteomicsPBP inactivation and OXA treatment resulted in altered protein compositions of Staphylococcal membrane vesicles
The engineered Staphylococcus aureus strain RN4220Δagr/EDⅢ was treated with 1/4 MIC of Oxacillin (OXA), or used to construct pbp3 and pbp4 gene mutant strain. Then, the membrane vesicles (MVs) of parent strain (ΔagrMVs), OXA-treated strain (Δagr/OXAMVs), and pbp3/pbp4 mutants (Δagr/OXAMVs) were harv...
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Rn4220 
2024-10-21 | PXD057038 |
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