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UnknownInterleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues.
Not available
S-EPMC3800471 | biostudies-literature
UnknownTrypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing.
Not available
S-EPMC3048136 | biostudies-literature
UnknownImpaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.
Not available
S-EPMC4346163 | biostudies-literature
ProteomicsA quantitative proteomics approach to monitor targeted protein degradation in M. smegmatis
Targeted protein degradation via the ubiquitin proteasome has been established in eukaryotes, however no application has been shown in bacteria so far. In the present work, selective protein degradation is shown using hetero bifunctional drugs, bringing substrates in close proximity to the bacterial...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Bacteria 
2022-08-12 | PXD021505 | Pride
Mycobacteria Targeted protein degradation Protease Tpd 
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
UnknownIsolation and functional characterization of murine prostate stem cells.
Not available
S-EPMC1716155 | biostudies-literature
ProteomicsA novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1
Phenotype-based screening can identify unique small molecules that elicit a desired cellular response, but additional approaches are required to characterize their targets and mechanisms of action. Here we show that a compound termed LCS3, which selectively impairs the growth of human lung adenocarc...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030294 | Pride
Lcs3 Thermal proteome profiling 
UnknownIatrogenic Critical Care Procedure Complication Boot Camp: A Simulation-based Pilot Study.
Not available
S-EPMC6457349 | biostudies-literature
UnknownThe centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles.
Not available
S-EPMC5760045 | biostudies-literature
UnknownOncogene-specific activation of tyrosine kinase networks during prostate cancer progression.
Not available
S-EPMC3277127 | biostudies-literature
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