Sort   by:  
 Page size 
ProteomicsWhole proteome analysis of mesonephric-derived cancers describes new potential biomarkers
Mesonephric carcinomas (ME) and Female Adnexal Tumors of probable Wolffian Origin (FATWO) are thought to derive from remnants of the Wolffian/mesonephric ducts – anlages of the male reproductive tract. Mesonephric-like carcinomas (MLC) show identical morphology to ME of the cervix, but occur in the ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD020879 | Pride
Tmt Mesonephric 
TranscriptomicsHigh temporal resolution profiling of U2OS fibroblasts
High-temporal resolution profiling was performed on U2OS fibroblasts to detect rhythmic transcripts Keywords: time course Samples were collected every hour for 48 hours from dexamethasone-synchronized U2OS cells. Cells synchronized with dexamethasone for 24 hours, and harvested from the 24th to 71...
ORGANISM(S): Homo sapiens 
2008-12-14 | E-GEOD-13949 | biostudies-arrayexpress
UnknownMolecular Signatures of Membrane Protein Complexes Underlying Muscular Dystrophy.
Not available
S-EPMC5083101 | biostudies-literature
TranscriptomicsA circadian gene expression atlas in mammals assayed by RNA-seq
To characterize the role of the circadian clock in mouse physiology and behavior, we used RNA-seq and DNA arrays to quantify the transcriptomes of 12 mouse organs over time. We found 43% of all protein coding genes showed circadian rhythms in transcription somewhere in the body, largely in an organ-...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-54651 | biostudies-arrayexpress
TranscriptomicsVariation in homeodomain DNA-binding revealed by high-resolution analysis of sequence preferences
Most homeodomains are unique within a genome, yet many are highly conserved across vast evolutionary distances, implying strong selection on their precise DNA-binding specificities. We determined the binding preferences of the majority (168) of mouse homeodomains to all possible 8-base sequences, re...
ORGANISM(S): Mus musculus 
2010-06-26 | E-GEOD-11239 | biostudies-arrayexpress
TranscriptomicsA library of yeast transcription factor motifs
The sequence specificity of DNA-binding proteins is the primary mechanism by which the cell recognizes genomic features. Here, we describe systematic determination of yeast transcription factor DNA-binding specificities. We obtained binding specificities for 112 DNA-binding proteins representing 19 ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-26 | E-GEOD-12349 | biostudies-arrayexpress
UnknownChemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.
Not available
S-EPMC4322257 | biostudies-literature
TranscriptomicsJnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and identify the cell-type involved ...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-40041 | biostudies-arrayexpress
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
TranscriptomicsInteraction between circadian clocks and metabolic physiology: implications for reproductive fitness
Circadian profiling of total RNA collected from wildtype and dnClk adult Drosophila fatbody 24 wild type and 12 dnClk samples, no replication
ORGANISM(S): Drosophila melanogaster 
2010-10-05 | E-GEOD-24503 | biostudies-arrayexpress
Sort   by:  
 Page size