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Molecular Biosciences and the Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX, USA (5)
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Klinik II für Innere Medizin: Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin Zentrum für Molekulare Medizin Köln (ZMMK) Uniklinik Köln Kerpener Str. 62 D-50937 Köln (3)
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Modification

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57.02146 (1)

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A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients

Organelles like lysosomes and synaptic vesicles are acidified by V-ATPases, which consist of a cytosolically-oriented V1 complex that hydrolyzes ATP and a membrane-embedded VO complex that pumps protons. In yeast, V1-VO association is facilitated by the RAVE complex, but how higher eukaryotes assemb...

ORGANISM(S): Homo sapiens (Human)

2025-05-20 | PXD064067 | Pride