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MetabolomicsThe Formation of Phenol and Indole Flavor Substances in Stinky Tofu Brine Based on Metabolism of Aromatic Amino Acids

Understanding the formation mechanism of the flavor compounds in stinky tofu brine is crucial for controlling the flavor quality of Changsha stinky tofu. Dynamic changes in associated bacteria, enzymes, and differential metabolites in the metabolic pathway of aromatic amino acids in brine were in...

2026-03-20 | MTBLS2849 | MetaboLights
GenomicsEarly B-cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue [ChIP-seq]
Examination of EBf1 binding by ChIP-seq in differentiated human adipose stromal cell (hASC) pre-adipocyte Pre-Adipocytes differentiated in-vitro were fixed in 1% formaldehyde for 15 min at room temperature and quenched for 5 min by adding glycine to a final concentration of 0.125 M. ChIP assays wer...
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-54889 | biostudies-arrayexpress
TranscriptomicsMicroarray comparison of anterior and posterior Drosophila wing imaginal disc cells
Signaling between cells in the Anterior (A) and Posterior (P) compartments directs Drosophila wing disc development and is dependent on expression of the homeodomain transcription factor Engrailed (En) in P cells. Downstream of en, posteriorly expressed Hedgehog (Hh) protein signals across the A/P ...
ORGANISM(S): Drosophila melanogaster 
2013-05-04 | E-GEOD-46601 | biostudies-arrayexpress
UnknownBRD1 deficiency affects SREBF1-related lipid metabolism through regulating H3K9ac/H3K9me3 transition to inhibit HCC progression.
Not available
S-EPMC11833140 | biostudies-literature
MetabolomicsMetabolomic insights into the browning of the peel of bagging 'Rui Xue' apple fruit

BACKGROUND: Bagging is one of the most important techniques for the production of high-quality fruits. In the act of cultivation, we found a new kind of browning in peel of the apple fruit that occurs before harvest and worsens during the storage period. There are many studies on...

2021-04-09 | MTBLS2384 | MetaboLights
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
ProteomicsMitochondrial dysfunction underlies cell cycle arrest and tubular hypoplasia in ClC-Kb-deficient Bartter syndrome mice
The pathogenesis of Bartter syndrome (BS) has long been attributed to decreased NaCl reabsorption in the thick ascending limb of Henle’s loop (TAL). By studying Clc-k2 (mouse ortholog of ClC-Kb)-knockout (Clc-k2-/-) mice, we recently uncovered an additional mechanism in which loss of transport funct...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-09 | PXD069389 | Pride
Metabolism Clc-k2 Mitochondria Cell cycle Bartter syndrome type 3 
TranscriptomicsGene expression profiles in different proglottids of Moniezia expansa
We used complementary DNA microarray to analyze the gene expression profiles in different proglottids of Moniezia expansa. A total of 4056 sequences including full length and partial complementary DNAs representing novel, known, and control genes were analyzed. We utilized cDNA array for detection o...
ORGANISM(S): Moniezia expansa 
2010-05-19 | E-GEOD-13892 | biostudies-arrayexpress
UnknownInvestigation on the mechanism of Shaoyao-Gancao Decoction in the treatment of gastric carcinoma based on network pharmacology and experimental verification.
Not available
S-EPMC9876642 | biostudies-literature
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