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OtherOmega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus.
Data from ProteomeXchange, PXD ID: PXD001277. File: 120329kw_JEnglish_JE12_2.mzml. Published as part of Front Genet. 2013 Oct 28;4:208 . From the Abstract: {{i}} Omega-3 fatty acid (n-3 FA) deficiency is an environmental risk factor for schizophrenia, yet characterization of the consequences of def...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320002655 | GPMDB
Resource Reanalysis 
ProteomicsHuman hippocampus LC-MSMS
Large-scale analysis of post-translational modification in the hippocampus of patients with Alzheimer's disease using pI shift and label free quantification without enrichment.
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD000950 | Pride
Human brain hippocampus lc-msms 
ProteomicsIn-depth protein profiling of mouse hippocampal postsynaptic density using data-independent acquisition proteomics
In the present study, we catalogued the proteome of postsynaptic density (PSD) derived from the hippocampus of three-week old (P19) mice. samples in 100 min gradient time.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-08-27 | MSV000084240 | MassIVE
ProteomicsMurine hippocampus after radiation LC-MSMS
The impact of low-dose ionizing radiation (IR) on human brain has recently attracted attention due to increased use of IR for diagnostic purposes. The aim of this study was to investigate low-dose radiation response in hippocampus. Female C57Bl/6 mice were irradiated with 0 (control), 0.063, 0.125 o...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-06 | PXD015729 | Pride
Ionizing radiation Hippocampus Brain Label-free proteomics Creb signaling Accelerated aging 
ProteomicsGlobal profiling of protein lactylation in Human hippocampi
Lysine lactylation (Kla) is a novel posttranslational modification, playing important roles in numerous biological processes, including transcription, metabolism, tumorigenesis and nervous system diseases. Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), researchers have identified l...
ORGANISM(S): Homo Sapiens 
2024-03-08 | PXD050470 |
ProteomicsProtoemics on HIPPOCAMPi FROM PARTIAL-BODY IRRADIATED MICE
Background: The brain undergoes ionizing radiation exposure in many clinical situations, particularly during radiotherapy for brain tumors. The critical role of hippocampus in the pathogenesis of radiation-induced neurocognitive dysfunction is well recognized. Aim: The goal of this study is to test...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024975 | Pride
2 weeks Shotgun proteomics 6 month Low radiation Hippocampus 
ProteomicsPTSD mouse anterior cingulate cortex proteome
Posttraumatic stress disorder (PTSD) is a prevalent psychiatric disorder. Several studies have attempted to characterize molecular alterations associated with PTSD, but most findings were limited to the investigation of specific cellular markers in the periphery or defined brain regions. In the curr...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-17 | PXD002271 | Pride
Ptsd Lc-msms Brain Mouse 
UnknownEffects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.
Not available
S-EPMC8579780 | biostudies-literature
ProteomicsExercise plasma dampens brain inflammation via clusterin and boosts memory
Physical exercise seems universally beneficial to human and animal health, slowing cognitive aging and neurodegeneration. Cognitive benefits are tied to increased plasticity and reduced inflammation within the hippocampus, yet little is known about the factors and mechanisms mediating these effects....
ORGANISM(S): Mus musculus (Mouse) 
2021-12-22 | PXD022262 | Pride
Lc-msms Mouse Plasma 
ProteomicsSynaptosome analysis Vps35l conditional knock-out mouse
Here, using synaptosome analysis of Vps35l-cKOSynapsin1, we provide a data-rich resource that reveals novel molecular insights into how VPS35L work in synapse.
ORGANISM(S): Mus musculus (Mouse) 
2026-05-05 | PXD064880 | Pride
Synapsin1 Vps35l Synaptosome Tmt label Lc-ms/ms 
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