Human hepatocellular carcinoma hepg2 cell

Show results for

Unknown (639)
Transcriptomics (170)
Genomics (105)
Proteomics (50)
Metabolomics (5)
Methylation profiling (3)
Other (1)

Organisms

Homo sapiens (222)
Mus musculus (10)
Rattus norvegicus (3)
synthetic construct (2)
Escherichia coli (1)
Betapolyomavirus hominis (1)
Betapolyomavirus macacae (1)
Human alphaherpesvirus 1 (1)
Human alphaherpesvirus 2 (1)
Human betaherpesvirus 5 (1)
Human gammaherpesvirus 8 (1)
Human immunodeficiency virus 1 (1)
JC polyomavirus (1)
Merkel cell polyomavirus (1)
Murid betaherpesvirus 1 (1)
Murid gammaherpesvirus 4 (1)
Mus musculus cytomegalovirus 2 (1)
human gammaherpesvirus 4 (1)
Trichinella spiralis (1)

Organisms

Homo sapiens (81)

Repository

biostudies-arrayexpress (137)
ENA (93)
geo (50)
pride (45)
MetaboLights (5)
MassIVE (3)
iProX (1)
jPOST (1)

Tissue

Hepatocyte (24)
Cell culture (20)
Liver (12)
Epithelial cell (3)
Blood plasma (2)
HepG2 cell (2)
Early embryonic cell (1)
Fibroblast (1)
HeLa cell (1)
Kidney (1)
Medulloblastoma cell (1)
Permanent cell line cell (1)
Skeletal muscle cell (1)

Disease

Hepatocellular carcinoma (19)
Liver cancer (3)
Adult hepatocellular carcinoma (2)
Brain cancer (1)
Glioblastoma (1)
Hepatitis B (1)
Hepatoblastoma (1)
Plasmodium falciparum malaria (1)

Technology Type

Mass Spectrometry (45)
Shotgun proteomics (24)
Bottom-up proteomics (7)
Affinity purification coupled with mass spectrometry proteomics (6)
Gel-based experiment (5)
Mass spectrometry (4)
Top-down proteomics (3)
Data-dependent acquisition (2)
Data-independent acquisition (2)
Mass spectrometry assay (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2500 (7)
NextSeq 550 (3)
Illumina HiSeq 2000 (3)
Illumina NovaSeq 6000 (2)
Illumina Human-12 v1 Expreesion BeadChip (1)
Axon GenePix4000B (1)
Illumina NovaSeq X (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
6520A Quadrupole Time-of-Flight LC/MS (1)
Q Exactive (1)
TripleTOF 6600 (1)
Exactive (Thermo Scientific) (1)
Gas Chromatography MS - positive (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - positive - reverse-phase (1)

Publication Date

2013 (26)
2025 (20)
2011 (19)
2022 (18)
2014 (18)
2026 (17)
2010 (16)
2015 (15)
2020 (13)
2012 (12)
2008 (12)
2016 (11)
2024 (8)
2021 (7)
2023 (6)
2017 (6)
2018 (6)
2019 (4)
2009 (3)
2007 (3)
2005 (2)

CHEBI ID

CHEBI:10022 (1)
CHEBI:104873 (1)
CHEBI:131416 (1)
CHEBI:131417 (1)
CHEBI:131428 (1)
CHEBI:131430 (1)
CHEBI:131438 (1)
CHEBI:131439 (1)
CHEBI:131440 (1)
CHEBI:131988 (1)
CHEBI:132579 (1)
CHEBI:132580 (1)
CHEBI:132773 (1)
CHEBI:133656 (1)
CHEBI:134240 (1)
CHEBI:134242 (1)
CHEBI:134266 (1)
CHEBI:134270 (1)
CHEBI:134303 (1)
CHEBI:134428 (1)
CHEBI:134487 (1)
CHEBI:134493 (1)
CHEBI:134494 (1)
CHEBI:134502 (1)
CHEBI:134541 (1)
CHEBI:134575 (1)
CHEBI:134579 (1)
CHEBI:134585 (1)
CHEBI:134587 (1)
CHEBI:134592 (1)

Metabolite Name

(1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,5-dihydroxy-4-[(E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxycyclohexane-1-carboxylic acid (1)
(2E,4E,8E)-7,13-dihydroxy-4,8,12-trimethyltetradeca-2,4,8-trienoic acid (1)
(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-((3-(benzo[d][1,3]dioxol-5-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (1)
(2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-((3-methoxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)thio)tetrahydro-2H-pyran-3,4,5-triyl triacetate (1)
(2S,3R)-2-(((S)-7-acetamido-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-10-yl)amino)-N-(5-chloropyridin-2-yl)-3-methylpentanamide (1)
(2S,3R,4S,5R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,6S,8R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol (1)
(3?,5?,9?,16?,18?,22?)-22-Acetoxy-16-hydroxy-13,28-epoxyoleanan-3-yl 6-deoxy-?-L-mannopyranosyl-(1->2)-?-D-galactopyranosyl-(1->3)-[?-D-glucopyranosyl-(1->2)]-?-D-glucopyran osiduronic acid_major (1)
(3S,4S,6aR,6bS,8R,8aR,12aS,14bR)-8-hydroxy-4,6a,6b,11,11,14b-hexamethyl-8a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid (1)
(3aS,3a1S,10bR,13S)-3a-ethyl-5-(methoxycarbonyl)-1,2,3,3a,3a1,4,6,11,12,13-decahydroindolizino[8,1-cd]carbazol-13-ium iodide (1)
(4R)-4-((5S,7R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (1)
(4R,E)-4-((3R,5R,6S,7R,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pent-2-enoic acid (1)
(6E)-2,6,10-trimethyldodeca-6,11-diene-2,3,10-triol_major (1)
(7S,9E,11S,12R,13S,14S,15S,16R,17S,18S,19E,21Z)-13-(acetyloxy)-15,17-dihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-26-(pyrrolidin-1-yl)-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1,3,5(28),9,19,21,25-heptae... (1)
(7S,9E,11S,12R,13S,14S,15S,16R,17S,18S,19E,21Z)-26-{4-[(furan-2-yl)carbonyl]piperazin-1-yl}-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1,3,5(28),9,19,2... (1)
(G)(NAM)-AemA;(3s-4)-(G)(NAM)-AemA (1)
(NAG)(NAM)-AeKA[3-NH2-GGGG] (1)
(NAG)(NAM)-AemAG;(3s-4)-(G)(NAM)-AemA (1)
(NAG)(NAM)-AqK;(G-G)-(NAG)(NAM)-None (1)
(NAG)(NAM)-AqKAA[3-NH2-n] (1)
(NAG)(NAM)-AqKAK[3-NH2-AA] (1)
(NAG)(NAM)-AqKA[3-NH2-d];(3br-4)-None-KA[3-NH2-d] (1)
(NAG)(NAM)-AqK[3-NH2-n];(G-G)-(NAG)(NAM)-None (1)
(NAG)(anNAM)-AqKAA[3-NH2-GG] (1)
(R)-4-((3R,5S,7S,8S,9S,10S,13R,14R,17R)-3,7,14-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (1)
(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7,12-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (1)
(R)-4-((8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (1)
(R)-4-((8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (1)
(S)-2-(((S)-7-acetamido-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-10-yl)amino)-4-(methylthio)-N-(2-(2-oxopyrrolidin-1-yl)ethyl)butanamide (1)
(S)-2-((R)-2-((S)-2-(2-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-hydroxy-4-oxo-4H-chromen-7-yl)oxy)acetamido)-3-phenylpropanamido)-4-methylpentanamido)-5-guanidinopentanoic acid (1)
(S)-4-((7-acetamido-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-10-yl)amino)-N-(benzo[d][1,3]dioxol-5-ylmethyl)butanamide (1)

First Public Date

2014 (18)
2021 (12)
2025 (11)
2026 (9)
2020 (8)
2022 (6)
2024 (5)
2018 (5)
2015 (5)
2019 (4)
2016 (4)
2017 (3)
2013 (2)
2023 (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (94)
RNA-seq of coding RNA (13)
ChIP-seq (6)
RNA-seq of total RNA (6)
Methylation profiling by array (4)
ChIP-chip by tiling array (3)
RNA-seq of non coding RNA (3)
RNAi profiling by array (2)
Other (2)
ChIP-chip by array (1)
RIP-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (63)
2023 (59)
2020 (57)
2017 (53)
2015 (52)
2021 (50)
2016 (50)
2014 (48)
2018 (48)
2013 (47)
2019 (46)
2024 (42)
2025 (36)
2011 (35)
2012 (25)
2010 (19)
2008 (15)
2009 (12)
2026 (9)
2005 (4)
2007 (2)
2006 (2)
2004 (1)
2003 (1)

Lab affiliation

Beijing institute of Lifeomics (2)
Functional Proteomics Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India (2)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (1)
Biozentrum Basel, University of Basel, Basel, Switzerland (1)
Center for Plant Aging Research, Institute for Basic Science, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea (1)
Centre for Liver Research, School of Digestive and Liver diseases, IPGME&R, Kolkata- 700020, West bengal , INDIA (1)
Centro de Química Estrutural, Instituto Superior Técnico, ULisboa, Lisboa, Portugal (1)
Charité – Universitätsmedizin Berlin (1)
Chief, Liver Diseases Branch, NIDDK, NIH, DHHS, U.S. Government (1)
College of Animal Sciences and Technology, Huazhong Agricultural University, China (1)
Dalian Key Laboratory on Chemicals Risk Control and Pollution Prevention Technology (1)
Department of Clinical Laboratory, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (1)
Department of Genetics, school of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, P.R. China (1)
Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China (1)
Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (1)
Department of Pathology, Medical University of Graz, 8010 Graz, Austria Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria (1)
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Hajipur, 844102, Bihar, India (1)
Department of Pharmacology Faculty of Health Sciences School of Medicine University of Pretoria (1)
Department of Vascular Biology and Thrombosis Research, Centre of Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, A-1090 Vienna, Austria (1)
Functional Proteomics Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India. (1)
Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Division of Cell Biology, Histology and Embryology, Medical University of Graz, 8010 Graz, Austria (1)
Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510623, China (1)
Head of the Curie Institute Mass Spectrometry Platform (1)
Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Broad Institute, Cambridge, Massachusetts, United States of America; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America. (1)
Imperial College London, The Francis Crick Institute (1)
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences, Pogodinskaya 10, Moscow, 119121, Russia (1)
Institution of hydrobiology，CAS (1)
Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH (1)
MOE Laboratory of Biosystem Homeostasis and Protection, College of Life Sciences, Zhejiang University; Hangzhou, Zhejiang, 310058, China (1)
Medizinisches Proteom-Center Ruhr-Universität Bochum Universitätsstr. 150 44801 Bochum Germany (1)

Previous page
1 / 98
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 98
Next page

Sort by:

Relevance

Page size

Real-world neonicotinoid mixture exposure reveals synergistic cytotoxicity and divergent pathway vulnerabilities in human cell lines

In this study, five human cell lines (A2780, Chang liver, HEK293T, HeLa, and HepG2) were used as models and exposed to mixtures of neonicotinoids (NEOs) and their metabolites. The mixture concentrations were prepared based on human biomonitoring data to reflect the actual detected levels of NEOs ...

2026-06-22 | MTBLS13896 | MetaboLights

Stable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture

Xenobiotics are ubiquitous in the environment and modified abundantly in the human body by phase I and II metabolism. Liquid chromatography coupled to high resolution mass spectrometry is a powerful tool to investigate these biotransformation products. Here, we present a workflow based on stable iso...

2020-04-14 | MTBLS1358 | MetaboLights

Single Cell triple omics sequencing reveals genetic and epigenetic heterogeneity in hepatocellular carcinoma

Single cell genome, DNA methylome, and transcriptome sequencing has been achieved separately. However, to analyze the regulation of RNA expression by genetic and epigenetic factors within an individual cell, it is necessary to analyze these omics simultaneously from the same single cell. Here we dev...

ORGANISM(S): Mus musculus

2016-03-01 | E-GEOD-65364 | biostudies-arrayexpress

HBX-HepG2 versus Control-HepG2 (no UV)

Mature microRNA expression profiling of HBx-expressing HepG2 cells versus Control cells. Free of UV sensitization. The mature microRNA expression profile of HBx-expressing HepG2 cells versus control cells in three independent biological repeated experiments (no UV). This study focuses only on human...

ORGANISM(S): Homo sapiens

2010-05-24 | E-GEOD-17474 | biostudies-arrayexpress

Chronic Hypoxia predicts Poor Prognosis in Hepatocellular Carcinoma

Background - Hepatocellular carcinomas (HCCs) are heterogeneous tumors with respect to etiology, cell of origin and biology. The course of the disease is unpredictable and is in part dependent on the tumor microenvironment. One of the microenvironmental factors is hypoxia, which is known to promote ...

ORGANISM(S): Homo sapiens

2010-07-20 | E-GEOD-15366 | biostudies-arrayexpress

Transcription profiling of by array of human hepatocellular carcinoma cells with RNAi knockdown of Wilm's Tumor 1 gene expression

The Wilms' tumor 1 gene (WT1) encodes a transcription factor involved in cell growth and development. As we previously reported WT1 expression is hardly detectable in normal hepatic tissue but is induced in liver cirrhosis. Although WT1 has been found to be overexpressed in a number of malignancies,...

ORGANISM(S): Homo sapiens

2008-10-26 | E-GEOD-12886 | biostudies-arrayexpress

The regulation of miRNA expression by DNA methylation in hepatocellular carcinoma

Emerging evidences indicate that microRNAs (miRNAs) are often deregulated and have fundamental roles in hepatocellular carcinoma (HCC). However, the mechanism underlying miRNA dysregulation in HCC is still elusive. In this report, we used an integrated analysis strategy combining methylated DNA immu...

ORGANISM(S): Homo sapiens

2015-08-05 | E-GEOD-49554 | biostudies-arrayexpress

Gene expression profiles for genetically engineered human hepatoma HepG2/8F_HS cells with or without heat treatment, cultured as monolayer or spheroids

We developed genetically engineered HepG2/8F_HS cells, in which eight liver-enriched transcription factor (LETF) genes—hepatocyte nuclear factor (HNF)-1α, HNF-1β, HNF-3β, HNF-4α, HNF-6, CCAAT/enhancer binding protein (C/EBP)-α, C/EBP-β and C/EBP-γ— under the control of TRE/PCMVmin promoter were intr...

ORGANISM(S): Homo sapiens

2022-04-04 | E-MTAB-11486 | biostudies-arrayexpress

Human Hepatocyte Proteome

Here we report a comprehensive proteomic analysis of purified human hepatocytes and a human hepatoma cell line HepG2. The complete dataset comprises 9,400 proteins and provides quantitative depiction of the proteomes of hepatocytes and HepG2 cells at the protein titer and copy number dimensions.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-03-07 | MSV000079562 | MassIVE

Gene expression of Listeria monocytogenes-infected HepG2 hepatocellular carcinoma in the presense of IL-17Aand IL-22

IL-17A and IL-22 induced several inflammation-induced genes and anti-microbial molecules including Pla2g2a and Lcn2 on HepG2 cells when the cells were treated with the cytokines before Listeria monocytogenes infection. HepG2 cells were treated with 50 ng/ml IL-17A and 10 ng/ml IL-22 before L. monocy...

ORGANISM(S): Homo sapiens

2015-12-17 | E-GEOD-71248 | biostudies-arrayexpress

Previous page
1 / 98
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 98
Next page

Sort by:

Relevance

Page size

974 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

First Public Date

Modification

Study type

Release Date

Lab affiliation

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets