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MetabolomicsModulating the developing gut microbiota with 2’-fucosyllactose and pooled human milk oligosaccharides

Synthetic human milk oligosaccharide (HMO) structures are used to supplement infant formula despite limited understanding of their impact on the developing gut microbiota. Here, we assess the impact of 2-fucosyllactose (2’FL) and pooled (p)HMOs on the composition and activity of cultured microbia...

2024-09-03 | MTBLS9853 | MetaboLights
MetabolomicsChanges in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth – Three Phases in Early Lactation and Progressive Individual Differences
Ursids (bears) in general, and giant pandas in particular, are highly altricial at birth. The components of bear milks and their changes with time may be uniquely adapted to nourish relatively immature neonates, protect them from pathogens, and support the maturation of neonatal digestive physiology...
2015-03-31 | MTBLS165 | MetaboLights
ProteomicsHuman Milk Oligosaccharide Interactions in Mouse Macrophage
Chemoproteomic profiling of Human Milk Oligosaccharide Interactions in Mouse Macrophages
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD035729 | Pride
Macrophage Raw264.7 Human milk oligosaccharide Chemoproteomics Diazirine Mouse 
TranscriptomicsComparative genomic hybridization by array of Bifodobacterium longum strains exhibiting various human milk oligosaccharide utilization phenotypes and host associations
Whole genome microarray comparisons (comparative genomic hybridizations) were used to associate genotypic biomarkers among 15 Bifidobacterium longum strains exhibiting various Human Milk Oligosaccharide utilization phenotypes and host associations.
ORGANISM(S): Bifidobacterium longum 
2010-10-21 | E-MEXP-2951 | biostudies-arrayexpress
ModelsIoannou2024 - Synthetic Human Infant Gut Microbial Community with Human Milk Oligosaccharides
These are genome-scale metabolic models used for understanding the metabolic activity and potential of a synthetic gut microbial community in the context of human milk oligossacharides.
2024-11-25 | MODEL2405300001 | BioModels
UnknownHuman milk oligosaccharide composition following supplementation with folic acid vs (6S)-5-methyltetrahydrofolic acid during pregnancy and mediation by human milk folate forms.
Not available
S-EPMC11003863 | biostudies-literature
TranscriptomicsRNA sequencing of Bifidobacterium longum subsp. infantis in response to various substrates
The purpose of this project was to determine the whole transcriptome response of Bifidobacterium longum subsp. Infantis to pooled and individual human milk oligosaccharides (HMO) relative to lactose Bacterial isolates grown on lactose, pooled human milk oligosaccharides (HMO), lacto-N-tetraose (LNT)...
ORGANISM(S): Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 
2015-10-28 | E-GEOD-58773 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of Bifidobacterium bifidum SC555 in response to various substrates
The purpose of this project was to determine the whole transcriptome response of Bifidobacterium bifidum SC555 to pooled and individual human milk oligosaccharides (HMO) relative to lactose Bacterial isolates grown on lactose, pooled human milk oligosaccharides (HMO), lacto-N-tetraose (LNT), lacto-N...
ORGANISM(S): Bifidobacterium bifidum 
2015-10-28 | E-GEOD-59053 | biostudies-arrayexpress
TranscriptomicsTranscriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection.
Purpose: To identify the impact of 2'-FL supplementation on adaptive response following extensive intestinal resection. Methods: Transcriptomic profiles were obtained from mice undergoing ileocecal recection (8-10 week old male mice) and again at 8 weeks post-surgery. At the time of resection and...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-72590 | biostudies-arrayexpress
UnknownAssociations between human milk EV-miRNAs and oligosaccharide concentrations in human milk.
Not available
S-EPMC11614774 | biostudies-literature
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