Sort   by:  
 Page size 
MetabolomicsMesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights
ProteomicsSecretome analysis of human bone marrow derived mesenchymal stromal cells
As an essential cellular component of the bone marrow (BM) microenvironment mesenchymal stromal cells (MSC) play a pivotal role for the physiological regulation of hematopoiesis, in particular through the secretion of cytokines and chemokines. Mass spectrometry (MS) facilitates the identification an...
ORGANISM(S): Homo sapiens (Human) 
2019-02-12 | PXD011643 | Pride
Bone marrow Mesenchymal stromal cells Hematopoiesis Secretome 
ProteomicsHuman mesenchimal stem cells secretome
The study reports for the first time a quantitative proteomic characterization of the secretome of human bone marrow derived MSC before and after stimulation with a panel of pro-inflammatory cytokines.
ORGANISM(S): Homo sapiens (Human) 
2017-08-11 | PXD005746 | Pride
Human msc secretome 
ProteomicsSecretome of hTERT-Immortalized Human Mesenchymal Stem Cells
The secretome of mesenchymal stromal cells (MSCs) can efficiently stimulate regener-ation and therefore is a tempting remedy for “cell-free cellular therapy”. However, the usage of primary MSC cultures as secretome-producers for translation studies has ob-vious obstacles, including rapid aging of MS...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD067843 | Pride
Htert Mesenchymal stem cells Human Secretome 
ProteomicsHuman Wharton’s jelly mesenchymal stem cells secretome inhibits human SARS-CoV-2 and avian IBV coronaviruses
Human SARS-CoV-2 and avian IBV are highly contagious and deadly coronaviruses causing devastating respiratory diseases in human and chicken, respectively. Lacking effective therapies exacerbates the disease associated with SARS-CoV-2 and IBV infections. Thus, novel therapeutic agents are in demand f...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD030966 | Pride
Human Proteomcis Mesenchymal stem cells Sars-cov-2 Lcmsms 
ProteomicsProteomic analysis of Wharton's jelly derived mesenchymal stem cell (WJ-MSC) secretome primed with inflammatory proteins
The immunomodulatory potential of mesenchymal stromal cells (MSCs) has led to their widespread exploration in treating various inflammatory conditions. MSCs sourced from adult tissues such as bone marrow, Wharton’s jelly, and adipose tissue are multipotent and exhibit strong stemness characteristics...
ORGANISM(S): Homo sapiens (Human) 
2026-02-17 | PXD064143 | Pride
Secretome Mesenchymal stem cell Priming 
UnknownMSC Secretome as a Promising Tool for Neuroprotection and Neuroregeneration in a Model of Intracerebral Hemorrhage.
Not available
S-EPMC8707464 | biostudies-literature
UnknownFine-tuning licensing strategies to boost MSC-based immunomodulatory secretome.
Not available
S-EPMC12004826 | biostudies-literature
UnknownComparative Effect of MSC Secretome to MSC Co-culture on Cardiomyocyte Gene Expression Under Hypoxic Conditions in vitro.
Not available
S-EPMC7571272 | biostudies-literature
ProteomicsThe Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-induced Cytotoxicity: Impact in Non-tumour Cells
Breast cancer remains one of the leading causes of death in women, being the chemotherapeutic agent doxorubicin (Dox) among the most widely standard chemotherapy options for its treatment. However, its effective use has been severely limited owing to its well-documented cardiotoxic side effect that ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029795 | Pride
Human  proteome  mesenchymal stem/stromal cells  secretome  3d cultures stem cell  cell culture 
Sort   by:  
 Page size