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TranscriptomicsComparative miRNA analysis between HPV (human papilloma virus)+ and HPV- oropharyngeal cancer
Oropharyngeal cancers have 2 main etiologies : High risk HPV (human papilloma virus) and tobacco/alcohol. The aim of this work is to find a miRNA signature specific to HPV induced oropharyngeal cancers
ORGANISM(S): Homo sapiens 
2015-05-12 | E-MTAB-3410 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse FVB/N wild type and transgenic Tg.AC mice to examine skin papilloma development
This study analyzes gene expression associated with papilloma development in Tg.AC v-Ha-ras transgenic mice and identifies novel genes and biological processes that may be critical to skin carcinogenesis in these mice. Epidermal abrasion was used to synchronously induce epidermal regeneration in FV...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-11136 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequencing and Novel HPV miRNA discovery in HPV cell lines and human tissue samples
Human papillomaviruses (HPV) preferentially infect keratinocytes of mucous membranes or skin and cause numerous benign and malignant lesions at different anatomical locations. A number of DNA viruses encode their own miRNAs as well. To date, no studies have been able to validate viral miRNAs in papi...
ORGANISM(S): Homo sapiens 
2013-08-18 | E-GEOD-42380 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human head and neck squamous cell carcinomas that are positive or negative for Human Papilloma Virus
Introduction: Human Papilloma Virus (HPV) is associated with a subset of head and neck squamous cell carcinoma (HNSCC), between 15% and 35% of HNSCC harboring HPV, almost exclusively of subtype 16. Demographic and exposure differences between HPV-positive (+) and negative (-) HNSCCs suggest that HPV...
ORGANISM(S): Homo sapiens 
2007-09-20 | E-GEOD-3292 | biostudies-arrayexpress
ClinicalProtecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination
A research project is currently being undertaken looking at Human Papilloma Virus (HPV) vaccination in special risk groups. It aims to see if young women with a chronic illness respond well to the HPV vaccine or whether they may require additional doses to ensure protective immunity. The four valent...
2077042 | ecrin-mdr-crc
TranscriptomicsMolecular evidence and gene expression profiles implicating involvement of Human Papilloma Virus in human retinoblastoma
Bilateral retinoblastoma has served as a critical model for studying genetic predisposition to cancer, however international incidence of unilateral retinoblastoma is variable across populations suggesting the involvement of environmental factors. DNA from Human Papilloma Virus (HPV) has been found ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-05-20 | E-GEOD-11488 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human immune dysregulation/tumor-associated gene changes in recurrent respiratory papillomatosis
The goal of this study was to determine the differential expression of specific genes within the papilloma tissues themselves and to characterize the array of host genes that might be important in the pathophysiology of recurrent respiratory papillomatosis. Experiment Overall Design: Total RNAs fr...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10935 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells before and after vaccination with human papilloma virus-like particle
Human papilloma (HPV) virus-like particle (VLP) vaccines were recently licensed. Though neutralizing antibody titers are thought to be the main effectors of protection against infection, early predictors of long-term efficacy are not yet defined and a comprehensive understanding of innate and adapt...
ORGANISM(S): Homo sapiens 
2008-11-22 | E-GEOD-13587 | biostudies-arrayexpress
TranscriptomicsOSCC Illumina GoldenGate Methylation
This study aims to compare the DNA methylome across a large cohort of oral squamous cell carcinoma and matched normal samples. DNA from 44 OSCCs and paired normal mucosa were analysed using Illumina GoldenGate methylation array. This data was correlated with extracapsular spread (extracapsular sprea...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-MTAB-1298 | biostudies-arrayexpress
GenomicsWNT ligands control initiation and progression of human papilloma-virus-driven squamous cell carcinoma
WNT ligands control initiation and progression of human papilloma-virus-driven squamous cell carcinoma
PRJNA427324 | ENA
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