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MetabolomicsMetabolomics of SLE-associated podocytes
To characterize metabolic changes in SLE-associated podocytes, 1 × 10^6 podocytes were stimulated for 24 hours with immune complexes (ICs) isolated from patients with systemic lupus erythematosus (SLE) or with IgG from healthy donors as a control. The cells were then collected and analyzed by untarg...
2026-09-23 | MTBLS15778 | MetaboLights
TranscriptomicsGene expression profiles of human iPSC derived podocytes
The gene expression profile of human iPSC derived podocytes were analyzed by utilizing NEPHS1-GFP knock-in human iPS cell line. The induced podocytes shows characteristic gene expression pattern that overlap with those of mouse and human podocytes in vivo. Kidney tissue was induced from human iPSC b...
ORGANISM(S): Homo sapiens 
2015-11-24 | E-GEOD-66969 | biostudies-arrayexpress
TranscriptomicsDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
In this work, we isolated and characterized a novel cell population derived from human amniotic fluid cells (hAKPC-P), and we differentiated them into podocytes. We used microarrays to study global changes in gene expression before and after differentiation in hAKPC-P and human immortalized podocyte...
ORGANISM(S): Homo sapiens 
2013-12-19 | E-GEOD-49439 | biostudies-arrayexpress
TranscriptomicsEffect of Growth hormone on podocytes
Transcriptome analysis of growth hormone dependant genes in glomerular podocytes Differentiated human glomerular podocytes in culture exposed to growth hormone for 0 min, 2 min, 5 min, 15 min, and 30 min. Total RNA is extracted and subjected to microarray analysis.
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21327 | biostudies-arrayexpress
GenomicsGene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes
Gene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes
PRJNA478696 | ENA
TranscriptomicsTranscription profiling of mouse Podocytes reveal use of FcRn to clear IgG from the glomerular basement membrane
The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here we provide evidence that an active transport mechanism exists t...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10017 | biostudies-arrayexpress
TranscriptomicsCyclodextrin protects podocytes in diabetic kidney disease [HumanWG-6 v3.0 array]
Analysis of gene expression changes in differentiated human podocytes treated with the serum from patients with (DKD+) or without (DKD-) diabetic kidney disease when compared to normal subjects (C). The hypothesis is that the three groups can be distinghed by their differential gene expression patte...
ORGANISM(S): Homo sapiens 
2013-07-11 | E-GEOD-46897 | biostudies-arrayexpress
TranscriptomicsCyclodextrin protects podocytes in diabetic kidney disease [HumanHT-12 V4.0 array]
Analysis of gene expression changes in differentiated human podocytes treated with the serum from patients with (DKD+) or without (DKD-) diabetic kidney disease when compared to normal subjects (C). The hypothesis is that the three groups can be distinghed by their differential gene expression patte...
ORGANISM(S): Homo sapiens 
2013-07-13 | E-GEOD-46899 | biostudies-arrayexpress
ProteomicsProteomic analyisis of cultured human podocytes stimulated with TNFa - supernatant
TNFa stimulated human cultured podocytes compared with unstimulated (vehicle control (VC)) podocytes. Incubation of podocytes with high concentrations of TNF alpha led to an overexpression of ICAM1 in particular. We studied this system as a comparator for organoids also stimulated with the same conc...
ORGANISM(S): Homo sapiens (Human) 
2023-05-19 | PXD032130 | Pride
Inflammation Podocytes Inflammatory response Cytokines 
ProteomicsProteomic analyisis of cultured human podocytes stimulated with TNFa - cell pellet
TNFa stimulated human cultured podocytes compared with unstimulated (vehicle control (VC)) podocytes. Incubation of podocytes with high concentrations of TNF alpha led to an overexpression of ICAM1 in particular. We studied this system as a comparator for organoids also stimulated with the same conc...
ORGANISM(S): Homo sapiens (Human) 
2023-05-19 | PXD032107 | Pride
Inflammation Podocytes Inflammatory response Cytokines 
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