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MetabolomicsProteomic and metabolomic profiling of acute and chronic stress events associated with military exercises.
By characterizing physiological changes that occur in warfighters during simulated combat, we can start to unravel the key biomolecular components that are linked to physical and cognitive performance. Viable field-based sensors for the warfighter must be rapid and noninvasive. In an effort to facil...
2023-12-05 | MTBLS5463 | MetaboLights
TranscriptomicsTranscriptome profiles derived from parallel venipuncture, dried blood spot (DBS), and saliva samples
Comparison of transcript abundance estimates derived from DBS vs saliva vs gold standard peripheral blood mononuclear cell (PBMC) samples. Gene expression profiling was conducted using parallel collection and assay of venipuncture blood samples (PBMC), DBS samples, and saliva. Data come from 58 comm...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-79269 | biostudies-arrayexpress
TranscriptomicsCorrelates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP)
Background: We seek to understand correlates of chronic stress and their influence on the development of substance use in a population-based cohort of young adults (OYSUP). Methodology: We evaluated clinical features, salivary RNA metrics and differential expression of candidate genes in unfraction...
ORGANISM(S): Homo sapiens 
2012-06-15 | E-GEOD-27144 | biostudies-arrayexpress
MetabolomicsFuel for the Damage Induced"""": Untargeted Metabolomics in Elite Rugby Union Match Play
The metabolic perturbations caused by competitive rugby are not well characterized. Our aim is to utilize untargeted metabolomics to develop appropriate interventions, based on the metabolic fluctuations that occur in response to this collision-based team sport. Seven members of an English Premiersh...
2021-09-06 | MTBLS2967 | MetaboLights
TranscriptomicsDNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm
Background: Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods that parallel controlled animal studies. Disaste...
ORGANISM(S): Homo sapiens 
2015-08-26 | E-GEOD-72354 | biostudies-arrayexpress
ProteomicsProteomic and Metabolomic Profiling of Acute and Chronic Stress Events Associated with Military Exercises
By characterizing physiological changes that occur in warfighters during simulated combat, we can start to unravel the key biomolecular components that are linked to physical and cognitive performance and fatigue. Viable field-based sensors for the warfighter must be rapid and noninvasive. In an ef...
ORGANISM(S): Homo sapiens (Human) 
2022-07-25 | PXD026680 | Pride
Human saliva stress 
MetabolomicsIdentification of Salivary Lipid Biomarkers for Noninvasive Diagnosis of Reflux Esophagitis via UHPLC-MS-based Lipidomics
Introduction Reflux esophagitis (RE) is a common upper gastrointestinal disorder, and its diagnosis currently relies primarily on invasive endoscopic examination. The lack of reliable non-invasive biomarkers substantially limits early detection and large-scale screening. Saliva represents a promisin...
2026-03-31 | MTBLS14198 | MetaboLights
ProteomicsProteomic Mapping of multifunctional complexes in triatomine Saliva
Salivary multiprotein complexes from Triatoma infestans, Triatoma dimidiata, Dipetalogaster maxima, Rhodnius prolixus, and Rhodnius neglectus were identified by Blue-Native-PAGE (BN-PAGE) coupled with liquid chromatography tandem mass spectrometry.
ORGANISM(S): Triatominae (ncbitaxon:70999) 
2020-03-18 | MSV000085118 | MassIVE
ProteomicsTop-down proteomics of human saliva in Alzheimer disease
Alzheimer disease (AD) is the most prevalent neurodegenerative disease and form of dementia in the elderly. It is characterized by the accumulation in the brain of misfolded proteins, inflammation and oxidative damage leading to region-specific loss of synaptic contacts and neuronal cell death. In t...
ORGANISM(S): Homo sapiens (Human) 
2021-05-24 | PXD021538 | Pride
S100a Salivary proteomics Alzheimer disease Oxidative stress Cystatins Α-defensins Antimicrobial peptides Thymosin β4 
Proteomicshuman saliva stress - Mixed Disorder As Reaction To Stress
Saliva samples were collected 24 hours prior to and no more than 20 minutes after modular egress training simulator (stressor).
ORGANISM(S): Homo sapiens (Human) 
2009-12-01 | PRD000164 | Pride
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