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TranscriptomicsAberrantly expressed lncRNAs in Primary Varicose Great Saphenous Veins
LncRNAs are key regulatory molecules involved in a variety of biological process and human diseases. However, the pathological effects of lncRNAs on primary varicose great saphenous veins (GSVs) remain unclear. In this study, we aimed at identifying aberrantly expressed lncRNAs involved in the preva...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-51260 | biostudies-arrayexpress
ProteomicsProteomic evaluation and comparison of native and decellularized human saphenous vein extracellular matrices
This project presents a label-free quantitative proteomic analysis of human saphenous vein (hSV) before and after decellularization, i.e. removal of cellular material using a CHAPS-based protocol. The study evaluated extracellular matrix preservation, vascular basement membrane composition changes, ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-17 | PXD068043 | Pride
Vascular tissue engineering Human saphenous vein Vascular graft Cardiovascular diseases Tissue decellularization Extracellular matrix Vascular basement membrane Regenerative medicine 
GenomicsmiRNA profiling of human saphenous vein pericyte exosomes
miRNA profiling of human saphenous vein pericyte exosomes
PRJNA487054 | ENA
GenomicsMechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors
Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors
PRJNA792820 | ENA
GenomicsTranscriptional changes upon overexpression of seven candidate miRNAs in human saphenous vein endothelial cells. [HSVEC]
Transcriptional changes upon overexpression of seven candidate miRNAs in human saphenous vein endothelial cells. [HSVEC]
PRJNA1063637 | ENA
TranscriptomicsTranscription profiling of human slow flow venous malformations and normal saphenous veins
Objective: Vascular malformations affect 3% of neonates. Venous malformations (VMs) are the largest group representing more than 50 % of cases. In hereditary forms of VMs gene mutations have been identified, but for the large group of spontaneous forms the primary cause and downstream dysregulated g...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7190 | biostudies-arrayexpress
OtherHuman Saphenous Vein Ex Vivo Culture as a Translational Model of Intimal Hyperplasia
BACKGROUND Intimal hyperplasia (IH) significantly limits the long-term patency of saphenous vein grafts following bypass surgery, with no reliable human-relevant models available to fully understand its complex pathogenesis. Previously, we established a static ex vivo culture model using human saphe...
ORGANISM(S): Homo sapiens 
2026-10-08 | GSE299685 | GEO
TranscriptomicsRNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation
Smooth muscle cell (SMC) phenotypic switching from a contractile to a synthetic state is implicated in diverse vascular pathologies, including neointimal formation. This study was designed to identify lncRNAs that may play a role in vascular pathologies. Primary smooth muscle cells cultured from sur...
ORGANISM(S): Homo sapiens 
2016-05-18 | E-GEOD-69637 | biostudies-arrayexpress
GenomicsTranscriptional changes upon overexpression of candidate miRNAs in human saphenous vein endothelial cells and human saphenous vein smooth muscle cells.
Transcriptional changes upon overexpression of candidate miRNAs in human saphenous vein endothelial cells and human saphenous vein smooth muscle cells.
PRJNA1063632 | ENA
OthermiRNA profiling of human saphenous vein pericyte exosomes
Human saphenous vein perciytes (hSVPs) were proved increase angiogenesis in mouse myocardial infarction model by producing and releasing miR-132, which has proangiogenic, prosurvival, and antifibrotic activity. To investigate whether their exosomes have a role in their proangiogenic activity, we exa...
ORGANISM(S): Homo sapiens 
2019-08-31 | GSE118855 | GEO
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