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MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
ProteomicsProteomic datasets for the identification of endometrial cancer in minimally invasive samples (cervico-vaginal fluid and blood plasma).
The aim of the underlying study was to identify protein signatures for the detection of endometrial cancer in minimally invasive samples such as cervico-vaginal fluid and blood plasma. Plasma and Delphi Screener-collected cervico-vaginal fluid samples were acquired from post-menopausal women who wer...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD050276 | Pride
Proteomics Endometrial cancer Swath Plasma Cervico-vaginal fluid 
ProteomicsComprehensive spectral library generation for identification and quantification of endometrial cancer protein biomarkers in cervico-vaginal fluid
This study focuses on the potential of detecting endometrial cancer based on the proteins and peptides expressed in cervico-vaginal fluid.Sequential window acquisition of all theoretical mass spectra (SWATH-MS), an accurate and reproducible platform for analysing biological samples, offers a technol...
ORGANISM(S): Homo sapiens (Human) 
2021-08-13 | PXD025925 | Pride
Endemetrial cancer Proteomics Spectral library Biomarkers Cervico-vaginal fluid 
MetabolomicsAmniotic-fluid metabolomics identifies phospholipid remodeling as a metabolic signature of intrauterine exposure in pregnancies with polycystic ovary syndrome
Background: Polycystic ovary syndrome is associated with metabolic and hormonal disturbances during pregnancy, but whether these alterations are reflected in the fetal intrauterine exposure environment remains incompletely understood. This study aimed to identify polycystic ovary syndrome-related in...
2026-07-25 | MTBLS14946 | MetaboLights
TranscriptomicsGenome-wide mRNA profiling for identification of specific body fluid markers
Genome-wide expression profiling of four kinds of body fluid samples (blood, saliva, semen and vaginal swab). The purpose of the present study was selection of specific mRNA markers for identification of the four body fluids. Results provide important information about gene expression level of each ...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-34844 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiles of menstrual blood and vaginal fluid
The ability to predict the type of tissues or cells from molecular profiles of crime scene samples has practical implications in forensics. In order to identify body fluid-specific DNA methylation changes, genome-wide DNA methylation profiling was carried out for body fluids including menstrual bloo...
ORGANISM(S): Homo sapiens 
2016-05-14 | E-GEOD-77283 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiles of forensically relevant body fluids [Set1]
The ability to predict tissue type and donor’s age from molecular profiles of crime scene samples has practical implications in forensics. In order to identify body fluid- and age-associated DNA methylation changes, genome-wide DNA methylation profiling was carried out for body fluids including bloo...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-59505 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiles of forensically relevant body fluids [Set3]
The ability to predict tissue type and donor’s age from molecular profiles of crime scene samples has practical implications in forensics. In order to identify body fluid- and age-associated DNA methylation changes, genome-wide DNA methylation profiling was carried out for body fluids including bloo...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-59508 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiles of forensically relevant body fluids [Set2]
The ability to predict tissue type and donor’s age from molecular profiles of crime scene samples has practical implications in forensics. In order to identify body fluid- and age-associated DNA methylation changes, genome-wide DNA methylation profiling was carried out for body fluids including bloo...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-59507 | biostudies-arrayexpress
ProteomicsVaginal secretory proteome dynamically changes across the early and mid-trimesters of pregnancy
This study investigates the dynamic alterations in high vaginal fluid (HVF) proteome and its correlation with physiological changes during progression of term pregnancy. The HVF samples were collected at three time points as defined as V1 (6-12 weeks), V2 (18-20 weeks) and V3 (26-28 weeks) and SWAT...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD021811 | Pride
Pregnancy Human vaginal fluid Longitudinal study Mrm Swath ms 
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