Human-chondrocyte-ms

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Unknown (13)
Proteomics (6)
Transcriptomics (4)
Metabolomics (2)

Organisms

Homo sapiens (4)
Andropogon gerardi (3)
Bacteria (3)
Canis lupus familiaris (3)
Clostridium perfringens (3)
Cnidaria (3)
Cricetulus griseus (3)
Eukaryota (3)
Fasciola (3)
Hepatitis B virus (3)
Human betaherpesvirus 5 (3)
Japanese encephalitis virus group (3)
Madurella mycetomatis (3)
Mesocricetus auratus (3)
Miscanthus x giganteus (3)
Mycobacterium tuberculosis (3)
Orthoflavivirus (3)
Panicum virgatum (3)
Platyhelminthes (3)
Pseudomonas aeruginosa AES-1R (3)
Rickettsia (3)
Saccharomyces cerevisiae (3)
Schizosaccharomyces pombe (3)
Severe acute respiratory syndrome coronavirus 2 (3)
Shigella (3)
Sorghastrum nutans (3)
Streptococcus dysgalactiae subsp. equisimilis SK1249 (3)
Streptococcus pneumoniae (3)
Rattus norvegicus (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (4)
pride (3)
MetaboLights (2)
iProX (1)
jPOST (1)
MassIVE (1)

Tissue

Articular chondrocyte (2)
Primary cell (2)

Disease

Osteoarthritis (2)

Technology Type

Mass Spectrometry (3)
Mass spectrometry (1)
Mass spectrometry assay (1)
Bottom-up proteomics (1)
Data-independent acquisition (1)
DiaPASEF (1)
Gel-based experiment (1)
Shotgun proteomics (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - positive - reverse phase (2)
Orbitrap Eclipse (1)
Orbitrap Exploris 480 (1)

Publication Date

2025 (4)
2007 (2)
2022 (2)
2016 (1)
2011 (1)
2026 (1)
2019 (1)

Metabolite Name

PC (18:5e/21:0) (1)
PC (20:3e/18:4) (1)
3-(3,4-dimethylphenyl)-3,4-dihydro-1,2,3-benzotriazin-4-one (1)
PC (20:4e/2:0) (1)
3-[(4-chlorophenyl)thio]-1-phenylprop-2-en-1-one (1)
PC (20:3e/18:5) (1)
PC (18:5e/20:4) (1)
N-(4-chlorophenyl)-N'-(2-phenoxyphenyl)urea (1)
6,7,8-trimethoxy-2H-chromen-2-one (1)
Quercetin-3¦Â-D-glucoside (1)
Lysine Butyrate (1)
3-(dimethylamino)-1-(5-methyl-3-phenyl-4-isoxazolyl)-2-propen-1-one (1)
2-{2-[4-(tert-butyl)phenyl]-4-hydroxy-1,3-thiazol-5-yl}acetic acid (1)
PC (22:6e/16:4) (1)
4-cyclopropyl-6-methoxy-1,3,5-triazin-2-amine (1)
PC (18:1e/2:0) (1)
PC (22:6e/18:4) (1)
PE (20:2/22:6) (1)
2-[(3S)-1-(4-Fluorobenzyl)-3-pyrrolidinyl]-5-methyl-1H-benzimidazole (1)
PC (18:3e/18:3) (1)
Ethyl 2-(tert-butyl)-3-chloro-5-cyano-6-morpholinoisonicotinate (1)
PE (16:1e/22:4) (1)
Auramine (1)
3-[(5-nitropyridin-2-yl)oxy]-1H-indazole (1)
PC (14:1e/18:0) (1)
4-(1H-pyrazol-1-yl)-N,N-bis(2-pyridinylmethyl)benzenesulfonamide (1)
3-{[(4-fluorophenyl)sulfonyl]amino}-5-phenylthiophene-2-carboxamide (1)
N-[2-(1,5-dimethyl-4-nitro-1H-pyrazol-3-yl)vinyl]-N,N-dimethylamine (1)
N1-methyl-5-methoxy-2-({2-[(methylamino)carbonyl]phenyl}thio)benzamide (1)
PC (20:5e/16:0) (1)

Study type

Transcription profiling by array (4)

Release Date

2021 (4)
2025 (3)
2007 (2)
2016 (1)
2011 (1)
2026 (1)
2023 (1)
2022 (1)
2020 (1)
2015 (1)
2010 (1)

Lab affiliation

Laboratory for Biomedical Mass Spectrometry, Newcastle University Biosciences Institute, Newcastle University, England (1)
Orthopedic Department, Peking University Third Hospital, Beijing 100191, P.R. China (1)
the first affiliated hospital, sun yat-sen university (1)

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S-EPMC2818349 | biostudies-literature

Adamts4 coordinates the transcriptomic profile of primary rat costal chondrocytes.

Not available

S-EPMC12933000 | biostudies-literature

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.

Not available

S-EPMC7991015 | biostudies-literature

Expansion and Delivery of Human Chondrocytes on Gelatin-Based Cell Carriers.

Not available

S-EPMC11942066 | biostudies-literature

Activation of Wnt/β-catenin signaling in subchondral bone osteoblast responced to hypoxia lead to osteoarthritis-like phenotype in articular chondrocyte

The crosstalk between the cartilage and subchondral bone plays a crucial role in the pathogenesis and progression of OA. The aim of this study was to identify soluble mediators released by osteoblasts that could induce the release of catabolic factors by chondrocytes. Global protein sequencing of su...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD021135 | Pride

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.

Not available

S-EPMC8365911 | biostudies-literature

Long non-coding RNA HOTTIP promotes CCL3 expression and induces cartilage degradation by sponging miR-455-3p

Long non-coding RNAs (lncRNAs) play pivotal roles in diseases such as osteoarthritis (OA). However, knowledge of the biological roles of lncRNAs is limited in OA. We aimed to explore the biological function and molecular mechanism of HOTTIP in chondrogenesis and cartilage degradation. We used the hu...

ORGANISM(S): Homo sapiens (Human)

2019-08-12 | PXD014988 | Pride

Human-chondrocyte-ms

A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress.

Not available

S-EPMC9718246 | biostudies-literature

LncRNA AC006064.4-201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1.

Not available

S-EPMC10099822 | biostudies-literature

Targeting Caspase-1 in osteoarthritis: multi-omics insights into the effects of VX-765 on human chondrocyte function and phenotype.

Not available

S-EPMC12532135 | biostudies-literature

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