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MetabolomicsThe murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria
Here, we report significant changes in the composition of the lung microbiome and metabolome of mice under immune suppression, infection of immunosuppressed mice with virulent and avirulent strains of the clinically important human-pathogenic fungus Aspergillus fumigatus, and treatment with the clin...
2025-07-04 | MTBLS12262 | MetaboLights
MetabolomicsA lipidomic human population and translational feeding study of hepatic steatosis and de novo lipogenesis (Murine liver assay)
Background: Diet is a major contributor to metabolic disease risk, but there is controversy as to whether increased incidences of diseases such as non-alcoholic fatty liver disease arise from consumption of saturated fats or free sugars. Our aims were to investigate whether a sub-set of TAGs were as...
2018-03-12 | MTBLS614 | MetaboLights
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
MetabolomicsIdentify putative volatile biomarkers of Valley fever using a murine lung infection model (Human studies)
Not available
ORGANISM(S): Homo sapiens 
ST002449 | MetabolomicsWorkbench
TranscriptomicsGlobal Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation
Purpose:The purpose of this study is to create unbiased, stage-specific transcriptomes by RNA-seq analyses of pure populations of both murine and human erythroblasts at distinct developmental stages. Methods: Recently developed FACS-based methods (Chen et al, PNAS, Liu et al, Blood, Hu et al Blood) ...
ORGANISM(S): Mus musculus 
2014-03-19 | E-GEOD-53983 | biostudies-arrayexpress
ProteomicsAP-MS analysis of murine and human norovirus VPg interactomes
The norovirus VPg protein is covalently linked to the viral genome in place of a 5' cap, and functions as a cap-substitute, capable of interacting with translation initiation factors. Following on from our previous study (Chung et. al. 2014, J. BIol. Chem.) we wished to determine the interactome of ...
ORGANISM(S): Homo sapiens (Human) 
2019-09-09 | PXD007585 | Pride
Norovirus Silac Hek293t Vpg Translation Calicivirus 
GenomicsTranscriptional Comparison of Human and Murine Retinal Neovascularization
Transcriptional Comparison of Human and Murine Retinal Neovascularization
PRJNA981457 | ENA
UnknownTherapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases.
Not available
S-EPMC8109019 | biostudies-literature
GenomicsBase editor induced mutation spectrum in GFP, human ATP1a1, human TP53BP1 and murine MyoD
Base editor induced mutation spectrum in GFP, human ATP1a1, human TP53BP1 and murine MyoD
PRJNA850939 | ENA
MetabolomicsNicotinamide Riboside is Uniquely Bioavailable in People and Mice
Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood, liver and heart NAD+ metabolism in people and mice. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single d...
2016-09-09 | MTBLS368 | MetaboLights
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