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TranscriptomicsmiRNA expression profiling in human mammary epithelial cell (HMEC) CD24-CD44+ and non-CD24-CD44+ cell populations
To understand the role of p53 in regulating stem cell population (CD24-CD44+) and stemness-associated miRNAs, we first compared miRNA expression profiles between human mammary epithelical cells knocked-down p53 and control cells. We then cross-referenced p53-regulated miRNAs with stemness-associated...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-25036 | biostudies-arrayexpress
TranscriptomicsThe role of p53 in the regulation of miRNA expression profiling
To understand the role of p53 in regulating stem cell population (CD24-CD44+) and stemness-associated miRNAs, we first compared miRNA expression profiles between human mammary epithelial cells knocked-down p53 and control cells. We then cross-referenced p53-regulated miRNAs with stemness-associated ...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-25035 | biostudies-arrayexpress
UnknownUnfolding analysis of the mature and unprocessed forms of Bacillus licheniformis γ-glutamyltranspeptidase.
Not available
S-EPMC3169692 | biostudies-literature
UnknownNonapnea Sleep Disorders and the Risk of Acute Kidney Injury: A Nationwide Population-Based Study.
Not available
S-EPMC4839913 | biostudies-literature
UnknownIsolated iridium oxide sites on modified carbon nitride for photoreforming of plastic derivatives.
Not available
S-EPMC11933312 | biostudies-literature
UnknownCombination With Low-dose Dextromethorphan Improves the Effect of Amlodipine Monotherapy in Clinical Hypertension: A First-in-human, Concept-proven, Prospective, Dose-escalation, Multicenter Study.
Not available
S-EPMC4998419 | biostudies-literature
ProteomicsTrafficking of Ectopic ATP Synthase via Mitochondrial Fission
Ectopic ATP synthase is a functional onco-protein increases cell proliferation when transported to plasma membrane of cancer cells. Our previous study performed large scale gene silencing screening indicated ER and mitochondrial transport pathways may lead to ectopic ATP synthase expression. Silenci...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD007036 | Pride
Ectopic atp synthases  proteome  protein trafficking  mitochondrial fission  image analysis 
ProteomicsNardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) develops through step-wise genetic and molecular alterations including Kras mutation and inactivation of apoptotic pathways. Here, we find that development of anoikis resistance and metastasis of KrasG12D-driven PDAC in mice is accelerated by deleting Plk3, ex...
ORGANISM(S): Homo sapiens (Human) 
2023-12-23 | PXD042993 | Pride
Plk3 Nardilysin (nrdc) metalloendopeptidase cleavage C-fos Anoikis Pancreatic ductal adenocarcinoma (pdac) Post-translational mechanism (ptm) Genetically engineered mouse models (gemms) Plk1 Kinase activation Metastasis 
UnknownVaccine Potential and Diversity of the Putative Cell Binding Factor (CBF, NMB0345/NEIS1825) Protein of Neisseria meningitidis.
Not available
S-EPMC4978444 | biostudies-literature
UnknownDistinct clinical phenotypes for Crohn's disease derived from patient surveys.
Not available
S-EPMC8034169 | biostudies-literature
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