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TranscriptomicsTestosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice
Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin (KISS1) do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Using micro-disse...
ORGANISM(S): Mus musculus 
2011-08-21 | E-GEOD-28383 | biostudies-arrayexpress
UnknownMacrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer.
Not available
S-EPMC7968518 | biostudies-literature
UnknownRON signalling promotes therapeutic resistance in ESR1 mutant breast cancer.
Not available
S-EPMC7782501 | biostudies-literature
UnknownIdentification of novel therapeutic targets in microdissected clear cell ovarian cancers.
Not available
S-EPMC3130734 | biostudies-literature
UnknownPhase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.
Not available
S-EPMC4135183 | biostudies-literature
UnknownHistone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.
Not available
S-EPMC6279577 | biostudies-literature
GenomicsEGAD00000000048
Sequencing data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000048 | EGA
GenomicsEGAD00000000049
RNA-SEQ data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000049 | EGA
GenomicsMutational evolution in a lobular breast tumour profiled at single nucleotide resolution
We have used next generation sequencing to sequence genomes (>43-fold coverage) and transcriptomes of an oestrogen-receptor-alpha-positive metastatic lobular breast cancer at depth. We found 32 somatic non-synonymous coding mutations present in the metastasis, and measured the frequency of these som...
EGAS00000000054 | EGA
UnknownThe testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent.
Not available
S-EPMC3111392 | biostudies-literature
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