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MetabolomicsHyaluronan catabolism supports the peritoneal disseminated metastasis of cancer through the glucuronic acid pathway
When disseminated into the peritoneal cavity at the very early stage, cancer cells must adapt to the glucose- and oxygen-limited environment in peritoneal fluid, yet the key molecular regulators remain undefined. Here, we reveal that early disseminated OC cells are ingeniously utilize hyaluronic aci...
2026-07-10 | MTBLS15007 | MetaboLights
ProteomicsProteomic analysis of Bacteroides thetaiotaomicron and Bacteroides acidifaciens following cultivation on hyaluronan and a standard substrate
This project investigates proteomic adaptations of Bacteroides thetaiotaomicron and Bacteroides acidifaciens in response to hyaluronan as the sole glycosaminoglycan carbon source. Both species were cultivated in a standard medium and in a hyaluronan-based minimal medium, and their proteomes were ana...
ORGANISM(S): Bacteroides acidifaciens Bacteroides thetaiotaomicron 
2026-02-23 | PXD067466 | Pride
Lc-ms Timstof pro Hyaluronan  bacteroides thetaiotaomicron  bacteroides acidifaciens  glycosaminoglycan metabolism 
TranscriptomicsDeletion of hyaluronan synthase 3 inhibits neointimal hyperplasia
Affymetrix Mouse Gene 2.0 ST Gene Expression Microarrays were used to analyze differentially expressed genes after carotid artery ligation. The aim of this experiment was to detect genes regulated in Has3 deficient as compared to wildtype controls that might be involved in neointimal hyperplasia. Ne...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-70410 | biostudies-arrayexpress
TranscriptomicsCultured cardiomyocytes treated with hyaluronan
Investigation of the role of hyaluronan in cardiomyocytes . The aims of the study were to determine if cardiomyocytes are capable of detecting hyaluronan and if then intrecellular signaling causes changes in gene expression. The study showed that cardiomyocytes can bind hyaluronan with following cha...
ORGANISM(S): Mus musculus 
2011-11-01 | GSE21675 | GEO
GenomicsGene expression profile of hyaluronan-induced cell clusters in multiple myeloma
Gene expression profile of hyaluronan-induced cell clusters in multiple myeloma
PRJNA782660 | ENA
GenomicsMyocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart
Myocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart
PRJNA1196984 | ENA
GenomicsMyocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart [RNASeq_Has2_knockout]
Myocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart [RNASeq_Has2_knockout]
PRJNA1199505 | ENA
GenomicsMyocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart [RNASeq_Has2_overexpression]
Myocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart [RNASeq_Has2_overexpression]
PRJNA1197474 | ENA
TranscriptomicsMyocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart
Background: The extracellular matrix provides organizational context for solid organs. During disease, such as acute myocardial infarction, the composition of the extracellular matrix changes remarkably. One of the most notable changes in the extracellular matrix is in the accumulation of collagen; ...
ORGANISM(S): Mus musculus 
2026-01-30 | GSE284092 | GEO
TranscriptomicsMyocardial Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production in the Failing Heart [RNASeq_Has2_overexpression]
Background: The extracellular matrix provides organizational context for solid organs. During disease, such as acute myocardial infarction, the composition of the extracellular matrix changes remarkably. One of the most notable changes in the extracellular matrix is in the accumulation of collagen; ...
ORGANISM(S): Mus musculus 
2026-01-30 | GSE284157 | GEO
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