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TranscriptomicsRegeneration of comparative genomic hybridization oligonucleotide microarrays with dimethylurea
Reuse of materials in DNA hybridization based methods has been known since the advent of Southern membranes. Array based comparative genomic hybridization is essentially Southern hybridization with multiple probes immobilized on a solid surface. We have shown that comparative genomic hybridization m...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-35740 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of mouse lymphoma model
Data underlying Sander et al., Oncogene 2005, June 20, Comparative genomic hybridization on mouse cDNA microarrays and its application to a murine lymphoma model. Includes both array CGH and expression data.
ORGANISM(S): Mus musculus 
2005-11-11 | E-SMDB-3419 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of several Enterococcus faecalis strains compared to strain V583
Gene content in various Enterococcus faecalis strains compared to E. faecalis V583. Strains have been compared to the V583 strain by comparative genomic hybridization using genome-wide PCR-based microarrays representing the V583 genome. Genes have been deemed "present" or "divergent" in the various ...
ORGANISM(S): Enterococcus faecalis 
2007-01-15 | E-MEXP-931 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human osteosarcoma cell lines to identify microaberrations
Background: Osteosarcoma (OS) is a very aggressive bone tumor characterized by highly abnormal complex karyotypes. With the improved resolution offered by array comparative genomic hybridization (array CGH) platforms, it is possible to readily detect cryptic microaberrations in genomic DNA. The i...
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-7077 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of gastric adenomas by array-based comparative genomic hybridization
In this study, we investigated CNAs of 20 gastric CIS (Vienna category 4.2) and 20 adenomas, including 7 low-grade adenomas (LGA; Vienna category 3) and 13 high-grade adenomas (HGA; Vienna category 4.1), by 244k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 gastric ad...
ORGANISM(S): Homo sapiens 
2010-06-18 | E-GEOD-19574 | biostudies-arrayexpress
TranscriptomicsNovel Lung Cancer-Related Genes Identified by a Non-Gapped Array-Comparative Genomic Hybridization Microarray in Asian and Caucasian Populations
This study constructed a non-gapped bacterial artificial chromosomes (BAC) array containing 3604 BAC clones covering 18 lung cancer-related chromosome imbalance hotspot regions. Using this specialized array, DNA from tumor and normal tissues of 40 Asian and 20 Caucasian non-small cell lung cancer (N...
ORGANISM(S): Homo sapiens 
2012-07-24 | E-GEOD-21276 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of follicular lymphoma by array comparative genomic hybridization
The secondary genetic events associated with follicular lymphoma (FL) progression are not well defined. We applied genome-wide BAC array comparative genomic hybridization to 106 diagnostic biopsies of FL to characterize regional genomic imbalances. Using an analytical approach that defined region...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-12393 | biostudies-arrayexpress
TranscriptomicsHigh-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes
Inflammatory breast cancer (IBC) is an aggressive form of BC poorly defined at the molecular level. We compared the molecular portraits of 63 IBC and 134 non-IBC (nIBC) clinical samples. Genomic imbalances of 49 IBCs and 124 nIBCs were determined using high-resolution array-comparative genomic hybri...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-23720 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Streptococcus suis strains - part 1
Comparative genome hybridization was used to study genomic diversity among S. suis strains in more detail. All strains were hybridized to an oligo-array based on the genome of P1/7 with P1/7 as an internal reference in all experiments.
ORGANISM(S): Streptococcus suis 
2010-12-31 | E-MEXP-2531 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of somatic cell hybrids ChX vs CHO, HPRT2 vs CHO
Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map- based positional cloning strategies in somatic cell hybrids to analyze genes responsible for recessive mutant phenotypes is often tedious, however, and remains a major obstacle in somatic...
ORGANISM(S): Homo sapiens 
2005-09-02 | E-SMDB-1524 | biostudies-arrayexpress
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