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UnknownAnalysis of RNA-containing compartments by hybridization and proximity labeling in cultured human cells.
Not available
S-EPMC8808287 | biostudies-literature
UnknownEnhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules.
Not available
S-EPMC12537909 | biostudies-literature
ProteomicsLabel-free LC-MS/MS analysis of proteins associated with expanded G4C2 hexanucleotide repeat-containing transcripts in human induced pluripotent stem cells
Proteins co-localizing with RNA targets of interest in human induced pluripotent stem cells (iPSCs) were identified using our recently optimized hybridization-proximity labeling approach (HyPro2) combined with label-free mass spectrometry. Briefly, fixed and permeabilized iPSCs from an ALS patient (...
ORGANISM(S): Homo sapiens (Human) 
2025-08-12 | PXD063192 | Pride
Actb Rna-protein interactions C9orf72 Pre-mrna Hybridization-proximity labeling 
UnknownHybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments.
Not available
S-EPMC8791277 | biostudies-literature
ProteomicsHyPro-MS analysis of proteins proximal to nuclear noncoding RNAs in HeLa cells
The ability of RNAs to form specific contacts with other macromolecules provides an important mechanism for subcellular compartmentalization. We developed a suite of hybridization-proximity (HyPro) labeling technologies for unbiased discovery of proteins (HyPro-MS) and transcripts (HyPro-seq) associ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-08 | PXD025264 | Pride
Human Hela cells Orbitrap fusion lumos tribrid Lc-ms/ms 
ProteomicsLabel-free LC-MS/MS analysis of proteins associated with specific RNAs in HeLa cells
Proteins co-localizing with RNA targets of interest in HeLa cells were identified using our recently optimized hybridization-proximity labeling approach (HyPro2) combined with label-free mass spectrometry. Briefly, fixed and permeabilized cells were hybridized with digoxigenin-labeled antisense olig...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD063191 | Pride
Actb Rna-protein interactions Lncrna Fus Pre-mrna Hybridization-proximity labeling Pnctr. 
TranscriptomicsNovel and highly recurrent chromosomal alterations in Sézary syndrome
This study was designed to identify highly recurrent genetic alterations typical of Sézary syndrome (Sz), an aggressive cutaneous T-cell lymphoma/leukemia, possibly revealing pathogenetic mechanisms and novel therapeutic targets. High-resolution array-based comparative genomic hybridization was don...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16384 | biostudies-arrayexpress
TranscriptomicsHyPro-seq analysis of HeLa and ARPE-19 cells
The ability of RNAs to form specific contacts with other macromolecules provides an important mechanism for subcellular compartmentalization. We developed a suite of hybridization-proximity (HyPro) labeling technologies for unbiased discovery of proteins (HyPro-MS) and transcripts (HyPro-seq) associ...
ORGANISM(S): Homo sapiens 
2021-11-05 | E-MTAB-10365 | biostudies-arrayexpress
UnknownRNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome.
Not available
S-EPMC6146591 | biostudies-literature
GenomicsEvaluation of miRNA expression in 14 different tissues by the RAKE technology
The short length of miRNAs results in a high dynamic range of melting temperatures and therefore impedes a proper selection of detection probes or optimized PCR primers. While miRNA microarrays allow for massive parallel and accurate relative measurement of all known miRNAs, they have so far been le...
ORGANISM(S): Sus scrofa 
2014-03-31 | GSE28140 | GEO
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