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ModelsFelixGarza2017 - Blue Light Treatment of Psoriasis (simplified)
FelixGarza2017 - Blue Light Treatment of Psoriasis (simplified) This model is described in the article: A Dynamic Model for Prediction of Psoriasis Management by Blue Light Irradiation. Félix Garza ZC, Liebmann J, Born M, Hilbers PA, van Riel NA. Front Physiol 2017; 8: 28 ...
2024-09-02 | BIOMD0000000695 | BioModels
ProteomicsA single mutation in NFU1 gene metabolically reprograms pulmonary artery smooth muscle cells
NFU1 is an iron-sulfur (Fe-S) scaffold protein, involved in Fe-S assembly and transfer to a range of mitochondrial metalloproteins. Patients with the NFU1G208C mutation develop pulmonary arterial hypertension (PAH) with 70% penetrance. Rats with NFU1G206C homozygous mutation demonstrated the PAH phe...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-08 | PXD015022 | Pride
Nfu1 Pulmonary arterial hypertension Hyper-proliferative Liver 
GenomicsImplication of EZH2 in the hyper-proliferative and apoptosis-resistant phenotype of pulmonary artery smooth muscle cells in PAH: a transcriptomic and proteomic approach
Implication of EZH2 in the hyper-proliferative and apoptosis-resistant phenotype of pulmonary artery smooth muscle cells in PAH: a transcriptomic and proteomic approach
PRJNA702549 | ENA
UnknownHyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.
Not available
S-EPMC4010457 | biostudies-literature
UnknownAnalysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells.
Not available
S-EPMC6642142 | biostudies-literature
TranscriptomicsTET2 guards against unchecked BATF3-induced CAR T cell expansion [RNA-seq]
Comparing transcriptional profiles of TET2 deficent hyper-proliferative CAR T cells and unedited CAR T cells
ORGANISM(S): Homo sapiens 
2022-12-30 | GSE220258 | GEO
GenomicsTET2 guards against unchecked BATF3-induced CAR T cell expansion [ATAC-seq]
Comparing genome accessibility profiles (ATACseq) of TET2 deficent hyper-proliferative CAR T cells and unedited CAR T cells
ORGANISM(S): Homo sapiens 
2022-12-30 | GSE220257 | GEO
TranscriptomicsRNAseq changes in mouse wound with or without time course treatment by Vemurafenib
BRAF inhibitors are highly effective therapies for patients with BRAF V600 mutated metastatic melanoma. Patients who receive BRAF inhibitors develop a variety of hyper-proliferative skin conditions, whose pathogenic basis is the paradoxical activation of the mitogen-activated protein kinase (MAPK) p...
ORGANISM(S): Mus musculus 
2016-07-29 | E-GEOD-74558 | biostudies-arrayexpress
TranscriptomicsRNAseq changes in mouse wound with or without time course treatment by Vemurafenib
BRAF inhibitors are highly effective therapies for patients with BRAF V600 mutated metastatic melanoma. Patients who receive BRAF inhibitors develop a variety of hyper-proliferative skin conditions, whose pathogenic basis is the paradoxical activation of the mitogen-activated protein kinase (MAPK) p...
ORGANISM(S): Mus musculus 
2016-07-29 | GSE74558 | GEO
TranscriptomicsGene expression alterations due to defective Fbw7-dependent cyclin E ubiquitination in bone marrow erythroid cells
A novel knock-in mouse model was reported (Minella et al., Genes Devel 2008) to have a mixed hyper-proliferative and defective maturation phenotype in the erythroid series. Microarray analyses were performed to identify gene expression alterations resulting from dysregulated cyclin E control. 
ORGANISM(S): Mus musculus 
2013-03-14 | GSE45135 | GEO
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