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UnknownEvolocumab safety and efficacy in hypercholesteremia patients with or without diabetes: a retrospective real-world analysis.
Not available
S-EPMC11783923 | biostudies-literature
TranscriptomicsTranscription profiling of human circulating monocytes from patients with familial hypercholesterolemia
Atherosclerosis is the major cause of death in industrialized countries. This disease has initially been characterized as a lipid disorder, but current concepts argue for an inflammatory disease, which develops in the background of hypercholesterolemia and other risk factors. In response to initial ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6054 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pig endothelial cells from animials fed high or low cholesterol diet shows brief hypercholesterolemia induces side-specific protective changes in pig aortic valve endothelia
The study demonstrates (i) spatial heterogeneity of endothelial responses to hypercholesterolemia in the aortic valve, (ii) that endothelial metabolism is not dysfunctional in early focal lipid insudation, and (iii) that protective endothelial pathways induced by hypercholesterolemia may initially i...
ORGANISM(S): Sus scrofa 
2009-11-16 | E-CBIL-47 | biostudies-arrayexpress
UnknownUrolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E-deficient mice.
Not available
S-EPMC11489441 | biostudies-literature
TranscriptomicsTranscription profiling of macrophages from Familial Hypercholesterolemia(FH) patients with tendon xanthomas (TX+) and without tendon xanthomas (TX-) to evaluate the gene expression profile in presence and absence of oxidized LDL
Total RNA pools from macrophages from Familial Hypercholesterolemia(FH) patients with tendon xanthomas (TX+) and without tendon xanthomas (TX-) were analyzed using Affymetrix oligonucleotide arrays (HGU133A) to evaluate the gene expression profile in presence and absence of oxidized LDL.
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-360 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pig reveals brief hypercholesterolemia induces changes in pig aortic endothelia
Hypercholesterolemia Study
ORGANISM(S): Sus scrofa 
2009-10-01 | E-CBIL-43 | biostudies-arrayexpress
TranscriptomicsNaringin the Major Grapefruit Flavonoid Specifically Affects Atherosclerosis Development in Diet-Induced Hypercholesterolemia in Mice
The objectif was to investigated the anti-atherogenic effects of nutritional supplementation of NAR in different mouse models of hypercholesterolemia and use transcriptomic approach to identify its molecular targets in the liver and aorta.
ORGANISM(S): Mus musculus 
2011-09-17 | E-MEXP-2932 | biostudies-arrayexpress
TranscriptomicsAn Antagonist of Toll-like Receptor 7 and 9 lowers cholesterol and reduces atherosclerosis in hyperlipidemic mice
The impact of a dual TLR7 and TLR9 antagonist on hypercholesteremia and atherosclerosis was evaluated in hyperlipidemic mice. Treatment with antagonist induced a dose dependent reduction of total cholesterol (TC) and LDL-cholesterol. Changes in Adiponectin, Leptin and free fatty acids levels were ob...
ORGANISM(S): Mus musculus 
2021-11-01 | GSE28125 | GEO
UnknownExendin-4 attenuates atherosclerosis progression via controlling hematopoietic stem/progenitor cell proliferation.
Not available
S-EPMC10478625 | biostudies-literature
UnknownExercise protects against PCB-induced inflammation and associated cardiovascular risk factors.
Not available
S-EPMC4503535 | biostudies-literature
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