Hyperoxaluria - OmicsDI

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Organisms

Rattus norvegicus (5)
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Repository

biostudies-arrayexpress (146)
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Tissue

Epithelial cell (1)

Disease

Normal (1)
Diabetes Mellitus (1)
Chronic kidney disease (1)
Primary hyperoxaluria type 1 (1)

Technology Type

Mass spectrometry assay (3)
Mass Spectrometry (3)
Bottom-up proteomics (2)
Data-dependent acquisition (2)
Gel-based experiment (1)

Instrument Platform

NextSeq 500 (2)
Q Exactive (2)
Liquid Chromatography MS - positive - reverse-phase (2)
Liquid Chromatography MS - negative - reverse-phase (2)
Axon- GenePix4000B (1)
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Liquid Chromatography MS - alternating - reverse phase (1)

Publication Date

2013 (32)
2011 (24)
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CHEBI ID

CHEBI:66860 (1)
CHEBI:66855 (1)
CHEBI:66854 (1)
CHEBI:66847 (1)
CHEBI:64424 (1)
CHEBI:64519 (1)
CHEBI:64525 (1)
CHEBI:64526 (1)
CHEBI:64446 (1)
CHEBI:66859 (1)
CHEBI:64504 (1)
CHEBI:64520 (1)
CHEBI:64523 (1)
CHEBI:64433 (1)
CHEBI:66857 (1)
CHEBI:64423 (1)
CHEBI:64516 (1)
CHEBI:64517 (1)
CHEBI:66849 (1)
CHEBI:66850 (1)
CHEBI:65303 (1)

Metabolite Name

Tulathromycin A (2)
N-Acetyl-L-glutamine (2)
5-methoxy-2-(2-methoxyphenyl)chromen-4-one (1)
2-hydroxy-4-(3-hydroxy-5-methylphenoxy)-6-methylbenzoic acid (1)
2-hydroxynaphthalene-1-carbaldehyde (1)
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one (1)
5,8-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one (1)
2-[({3-[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoyloxy]-4,5-dihydroxyphenyl}(hydroxy)methylidene)amino]acetic acid (1)
2-amino-4'-hydroxy-Propiophenone (1)
Alpha-Fluoro-beta-ureidopropionic acid (1)
(4S,5S,10R)-4-Hydroxy-5-methoxy-10-methyl-2,7-oxecanedione (1)
3,4,5-trihydroxy-6-[(2-oxo-2H-chromen-4-yl)oxy]oxane-2-carboxylic acid (1)
5-(hydroxymethyl)- 2-Furancarboxylic acid (1)
Methyl (E)-11-(5-carbamoyl-4-oxo-1H-pyridin-2-yl)undec-10-enoate (1)
(2R,3S,4S,5R,6R)-2-methylol-6-phenethoxy-tetrahydropyran-3,4,5-triol (1)
8-{(1S,5R)-4-Oxo-5-[(2Z)-2-penten-1-yl]-2-cyclopenten-1-yl}octanoic acid (1)
Depo-Medrol (1)
3-(1,3-benzodioxol-5-yl)propane-1,2-diol (1)
3-hydroxy-N-(2-oxooxolan-3-yl)octanamide (1)
3,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one (1)
2-Aminoheptane (1)
2-(1-{[(1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-hydroxy-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetic acid (1)
3-[2-[2-(carboxymethoxy)ethoxy]ethoxymethyl]heptanoic acid (1)
8-(2,3-dihydroxy-3-methylbutyl)-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one (1)
(E)-11-(5-carbamoyl-4-oxo-1H-pyridin-2-yl)undec-10-enoic acid (1)
(2S)-1-acetylpyrrolidine-2-carboxylic acid (1)
2-[N-(ethoxymethyl)-2-ethyl-6-methylanilino]-2-oxoacetic acid (1)
5-hydroxy-8,8-dimethyl-6-(2-methylbutanoyl)-4-phenylpyrano[2,3-h]chromen-2-one (1)
6-[(6-{[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-3,4,5-trihydroxyoxan-2-yl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid (1)
{2-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-6-methyl-5-oxo-3-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-4-yl}oxidanesulfonic acid (1)

First Public Date

2023 (4)
2026 (3)
2025 (3)
2024 (3)
2018 (3)
2017 (3)
2015 (2)
2022 (1)
2014 (1)

Study status

Recruiting (1)

Study type

ChIP-chip by tiling array (46)
Transcription profiling by array (34)
ChIP-seq (25)
RNA-seq of coding RNA (13)
Other (8)
RNA-seq of non coding RNA (6)
Transcription profiling by tiling array (4)
ChIP-chip by array (3)
RNAi profiling by array (2)
CUT&TAG (1)
Comparative genomic hybridization by array (1)
ATAC-seq (1)
DNA-seq (1)
RNA-seq of total RNA (1)
Observational (1)

Release Date

2022 (43)
2013 (38)
2025 (36)
2023 (33)
2021 (31)
2011 (30)
2024 (30)
2014 (28)
2012 (26)
2010 (26)
2015 (22)
2020 (18)
2016 (16)
2019 (13)
2026 (10)
2007 (10)
2018 (9)
2017 (8)
2009 (6)
2008 (6)
2006 (3)

Lab affiliation

Institute of Microbiology,The Czech Academy of Sciences (1)
Laboratory of Structural Biology and Cell Signaling, Institute of Microbiology of the Czech Acad Sci, Prumyslova 595, 252 50 Vestec, Czech Republic (1)
University of Chicago Pritzker School of Medicine, Section of Nephrology, Chicago, IL 60637 USA (1)

Location

Belgium (1)

Tags

xref:PubMed:38182795 (2)
xref:PubMed:39427033 (1)
xref:PubMed:38577102 (1)
xref:PubMed:29091707 (1)
xref:PubMed:23091645 (1)
xref:PubMed:24598804 (1)

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Genome-wide analysis of renal gene expression during hyperoxaluria development

Previous studies have proposed that production of reactive oxygen species (ROS) is an important contributor to renal injury and inflammation following exposure to oxalate or calcium-oxalate crystals. The present study was conducted to determine, utilizing global transcriptome analyses, if the NADPH...

ORGANISM(S): Rattus norvegicus

2012-12-20 | E-GEOD-36446 | biostudies-arrayexpress

Improving Treatment Options for Primary Hyperoxaluria.

Not available

S-EPMC9329168 | biostudies-literature

Phenotypic and functional analysis of human SLC26A6 variants in patients with familial hyperoxaluria and calcium oxalate nephrolithiasis.

Not available

S-EPMC2710965 | biostudies-literature

Not available

S-EPMC8956551 | biostudies-literature

Posttransplant recurrence of calcium oxalate crystals in patients with primary hyperoxaluria: Incidence, risk factors, and effect on renal allograft function.

Not available