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ProteomicsComparative transcriptomic and proteomic analyses provide insights into functional genes for hypoxic adaptation in embryos of Tibetan chickens
Tibetan chickens, a unique plateau breed, have good performances to adapt to high-altitude hypoxic environments. A number of positively selected genes have been reported in Tibetan chickens; however, the mechanisms of gene expression for hypoxia adaptation are not fully understood. In the present st...
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-08 | PXD012607 | Pride
Tibetan chicken Cam Transcriptome Proteome Hypoxic adaption 
ProteomicsProteins and pathways associated with hypoxic adaption of yaks based on proteome data
Responses to hypoxia and adaptive mechanisms have attracted increased attention in many fields. The aim of current study was to investigate the lung tissue proteomic data of yak hypoxic adaption. Proteomic data were generated from lung tissue of the 9 yaks living at three different altitudes with Za...
ORGANISM(S): Bos Taurus 
2021-06-21 | PXD026847 |
GenomicsNFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung [SMC]
NFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung [SMC]
PRJNA739164 | ENA
GenomicsNFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung [normoxia vs hypoxia]
NFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung [normoxia vs hypoxia]
PRJNA739162 | ENA
GenomicsNFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung
NFAT5/TonEBP controls metabolic adaption and tone of pulmonary vascular smooth muscle cells in the hypoxic lung
PRJNA739156 | ENA
UnknownThe RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs.
Not available
S-EPMC7272636 | biostudies-literature
TranscriptomicsTranscriptome partitioning for mRNA translation in hypoxia
Protein synthesis belongs to the most energy consuming processes in the cell. Lowering oxygen tension below normal (hypoxia) causes a rapid inhibition of global mRNA translation due to the decreased availability of energy. Interestingly, subsets of mRNAs pursue active translation under such circumst...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-49029 | biostudies-arrayexpress
TranscriptomicsMultiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes
The central nervous system normally functions at O2 levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O2-dependent cellular adaptation. We analyzed the reactivi...
ORGANISM(S): Rattus norvegicus 
2012-09-20 | E-GEOD-29296 | biostudies-arrayexpress
UnknownFusion of Normoxic- and Hypoxic-Preconditioned Myoblasts Leads to Increased Hypertrophy.
Not available
S-EPMC8947054 | biostudies-literature
TranscriptomicsComparative transcriptomic and proteomic analyses provide insights into functional genes for hypoxic adaptation in embryos of Tibetan chickens
Background/Aims: Tibetan chickens, a unique plateau breed, have good performances to adapt to high-altitude hypoxic environments. A number of positively selected genes have been reported in Tibetan chickens; however, the mechanisms of gene expression for hypoxia adaptation are not fully understood. ...
ORGANISM(S): Gallus gallus 
2020-07-13 | GSE126082 | GEO
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