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ProteomicsMolecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1
During collagen biosynthesis, lysine residues undergo extensive post-translational modifications through the alternate action of two distinct metal ion-dependent enzyme families (i.e., LH/PLODs and GLT25D/COLGALT), ultimately producing the highly conserved alpha-(1,2)-glucosyl-beta-(1,2)-galactosyl-...
ORGANISM(S): Homo sapiens (Human) 
2025-03-05 | PXD061021 | Pride
Glycosyltransferase Collagen biosynthesis  extracellular matrix  post-translational modifications 
Proteomics2) Twisting Urea- to Imide-Based Mass Spectrometry-Cleavable Cross-Linkers to Embed Affinity Tags
Disuccinimidyl dibutyric urea (DSBU) is a mass spectrometry (MS)-cleavable cross-linker that has been applied to multiple applications in structural biology, ranging from isolated protein complexes to comprehensive system-wide interactomics. DSBU facilitates a rapid and reliable identification of cr...
ORGANISM(S): Homo sapiens (Human) 
2024-09-03 | PXD050960 | Pride
Protein-protein interactions  structural proteomics Dsbu Cross-linking mass spectrometry  xlms Idp Intrinsically disordered protein 
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