Sort   by:  
 Page size 
Study expression effects of single transcription factor deletions.
ORGANISM(S): Saccharomyces cerevisiae 
Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated factor achieves its regulatory specificity. In these cases, a systems approach may distin...
ORGANISM(S): Saccharomyces cerevisiae 
HIV-associated dementia (HAD) is a syndrome occurring in HIV-infected patients with advanced disease that likely develops as a result of macrophage and microglial activation as well as other immune events triggered by virus in the central nervous system. The most relevant experimental model of HAD, ...
ORGANISM(S): Macaca mulatta 
Recent studies have documented genome-wide binding patterns of transcriptional regulators and their associated epigenetic marks in hematopoietic cell lineages. In order to determine how epigenetic marks are established and maintained during developmental progression, we have generated long-term cult...
ORGANISM(S): Mus musculus 
Gene expression profiles of transcription factor deletion strains (S.cerevisiae) perturbed with 0.03% methyl-methanesulfonate for 60 minutes
ORGANISM(S): Saccharomyces cerevisiae 
Genome-wide promoter-binding analysis of transcription factors in S.cerevisiae cells perturbed with 0.03% methyl-methanesulfonate for 60 minutes
ORGANISM(S): Saccharomyces cerevisiae 
The parent S. cerevisiae strain, BY4741, and specific gene deletions of the parent S.cerevisiae strain BY4741 were treated with 100uM NaAsO2 (AsIII) for 2h and compared to the untreated counterpart (yap1Î? vs. yap1Î? 2h 100uM AsIII, cad1Î? vs. cad1Î? 2h 100uMAsIII, rpn4Î? vs. rpn4Î? 2h 100uM AsIII, ...
ORGANISM(S): Saccharomyces cerevisiae 
It is now established that the transcription factors E2A, EBF1 and FoxoM-BM- 1 play critical roles in B cell development. Here we show that E2A and EBF1 bound regulatory elements present in the Foxo1 locus. E2A and EBF1 as well as E2A and Foxo1, in turn, were wired together by a vast spectrum of cis...
ORGANISM(S): Mus musculus 
Sort   by:  
 Page size