Sort   by:  
 Page size 
MetabolomicsMetabolomic profiling of IDH1 mutation
Not available
ORGANISM(S): Homo sapiens 
ST000821 | MetabolomicsWorkbench
MetabolomicsMetabolomic profiling of IDH1 mutation (part II)
Not available
ORGANISM(S): Homo sapiens 
ST000822 | MetabolomicsWorkbench
GenomicsIdh1-R132H mutation increases murine hematopoietic progenitors and alters epigenetics.
Mutations in the IDH1 and IDH2 genes encoding isocitrate dehydrogenases are frequent in human glioblastomas1 and cytogenetically normal acute myeloid leukemias (AML)2. These alterations are gain-of-function mutations in that they drive the synthesis of the M-bM-^@M-^\oncometaboliteM-bM-^@M-^] R-2-hy...
ORGANISM(S): Mus musculus 
2012-07-22 | E-GEOD-38687 | biostudies-arrayexpress
ProteomicsEffects of the IDH1 R132H mutation on the energy metabolism: a comparison between tissue and corresponding primary glioma cell cultures
The R132H mutation in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) is the most important prognostic factor for survival of glioma patients. This resulted in many studies investigating the effects of this mutation, including those on energy metabolism. This led to the discovery of a panel o...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD024019 | Pride
Idh1 r132h mutation Cell cultures Glioma Proteomics Energy metabolism 
ProteomicsEffects of the IDH1 R132H mutation on the energy metabolism: a comparison between tissue and corresponding primary glioma cell cultures
The R132H mutation in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) is the most important prognostic factor for survival of glioma patients. This resulted in many studies investigating the effects of this mutation, including those on energy metabolism. This led to the discovery of a panel o...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD024009 | Pride
Idh1 r132h mutation Cell cultures Glioma Proteomics Energy metabolism 
ProteomicsMetabolic changes related to the IDH1 mutation in gliomas preserve TCA-cycle activity: an investigation at the protein level
The discovery of the IDH1 R132H (IDH1 mut) mutation in low-grade glioma and the associated change in function of the IDH1 enzyme has increased the interest in glioma metabolism. In an earlier study, we found that changes in expression of genes involved in the aerobic glycolysis and the TCA-cycle are...
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD016697 | Pride
Proteomics Glioma Idh1 mutation 
TranscriptomicsGenome-wide analysis of mRNA expression alterations of sorted LysM-KI LSK cells versus control LSK cells
Microarrays were used to examine gene expression changes between bone marrow isolated haematopoeietic cell populations (LSK cells: Lin-Sca1+cKit+) populations of control and mutant (LysM-KI) mice. The LysM-KI mouse is a murine model which expresses an Idh1 (isocitrate dehydrogenase 1) mutation (I...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-38589 | biostudies-arrayexpress
TranscriptomicsDNA methylation alterations and transcriptional gene silencing induced by IDH1 R132H mutation
This SuperSeries is composed of the following subset Series: GSE31126: DNA methylation alterations and transcriptional gene silencing induced by IDH1 R132H mutation [Affymetrix] GSE31133: DNA methylation alterations and transcriptional gene silencing induced by IDH1 R132H mutation [Illumina] Refer t...
ORGANISM(S): Homo sapiens 
2012-08-12 | E-GEOD-31134 | biostudies-arrayexpress
UnknownIDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
Not available
S-EPMC5438698 | biostudies-literature
ProteomicsMetabolic changes related to the IDH1 mutation in gliomas preserve TCA-cycle activity: an investigation at the protein level
The discovery of the IDH1 R132H (IDH1 mut) mutation in low-grade glioma and the associated change in function of the IDH1 enzyme has increased the interest in glioma metabolism. In an earlier study, we found that changes in expression of genes involved in the aerobic glycolysis and the TCA-cycle are...
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD016698 | Pride
Metabolism Idh1 Proteomics Glioma 
Sort   by:  
 Page size