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TranscriptomicsTranscription profiling of mouse small intestine intraepithelial lymphocytes (IEL) vs. TCR ab+ CD8b+ and TCR gd+ cells
Mouse small intestine intraepithelial lymphocytes (IEL) that express a ab TCR and CD8aa homodimers are an enigmatic T cell subset, as their specificity and in vivo function remain to be defined. To gain insight into the nature of these cells, we performed global gene expression profiling using micr...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5355 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse small intestinal γδ intraepithelial lymphocytes
The mammalian gastrointestinal tract harbors thousands of bacterial species that include symbionts as well as potential pathogens. The immune responses that limit access of these bacteria to underlying tissue remain poorly defined. In this study, we used microarrays to uncover the transcriptional re...
ORGANISM(S): Mus musculus 
2011-04-06 | E-GEOD-28437 | biostudies-arrayexpress
GenomicsGene expression in WT and LRF-deficient thymic IEL precusors (IELp) and their progeny CD8aa IEL
Gene expression in WT and LRF-deficient thymic IEL precusors (IELp) and their progeny CD8aa IEL
PRJNA630671 | ENA
GenomicsScRNAseq of human IEL and LPL T lymphocytes
ScRNAseq of human IEL and LPL T lymphocytes
PRJNA661452 | ENA
TranscriptomicsGene expression analysis of CD122HI versus CD122LO Vγ7+ murine small intestinal IEL at 14-17 days of age
Background: Recently have found that Btnl1 expressed by murine enterocytes shapes the local TCR-Vγ7+ compartment by driving their clonotypic expansion and phenotypic maturation from CD122LO to CD122HI Vγ7+ cells. The neonatal (D14-17) murine small intestinal epithelium is enriched for Vγ7+ IEL d...
ORGANISM(S): Mus musculus 
2016-08-11 | E-GEOD-85422 | biostudies-arrayexpress
ProteomicsComprehensive proteomics analyses of IL-15 driven activation of intestinal intraepithelial lymphocytes
Intestinal intraepithelial lymphocytes (IEL) are an abundant population of tissue-resident T cells that protect the gut from pathogens and maintain intestinal homeostasis. The cytokine IL-15 is trans-presented by epithelial cells to IEL in complex with the IL-15 receptor α chain (IL-15Rα) and plays ...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-10 | PXD025891 | Pride
Intraepithelial lymphocytes  interleukin-15  quantitative proteomics  coeliac disease  histone ruler  lfq 
GenomicsColon IEL gene expression
Colon IEL gene expression
PRJNA811689 | ENA
GenomicsSingle-cell Gene expression of WT CD8aa IEL and LRF-deficient CD8aa splenocytes
Single-cell Gene expression of WT CD8aa IEL and LRF-deficient CD8aa splenocytes
PRJNA772760 | ENA
TranscriptomicsGene expression in WT and LRF-deficient thymic IEL precusors (IELp) and their progeny CD8aa IEL
Gene expression of IELp and CD8aa IEL was determined by RNAseq
ORGANISM(S): Mus musculus 
2022-03-30 | GSE149943 | GEO
TranscriptomicsIn vitro activation of Btnl-1 transduced MODE-K cells with different stimuli
The experiment was designed to assess how intestinal epithelial cells respond to different soluble factors produced by intraepithelial lymphocytes (IEL) and how this response is altered when the epithelial cells express Btnl1. Total RNA of MODE-K cells transduced with Btnl1-GFP or GFP alone and stim...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-63364 | biostudies-arrayexpress
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