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By profiling lncRNA expression changes during human skin wound healing and screening lncRNA functions, we identified SNHG26 as a pivotal regulator in keratinocyte progenitors underpinning this phase transition. we performed RNA pull-down assay in human keratinocyte progenitors and found SNHG26 inter...
ORGANISM(S): Homo sapiens (Human) 
2024-08-28 | PXD055235 | Pride
Exploring ILF2 regulatory genes by next-generation sequencing
T cell activation leads to dramatic changes in cellular phenotype. We used CD3/CD28-activated human CD4 T cells to study how RNA binding proteins define the post-transcriptional landscape. Using RIPseq, we identified the RNA interactome of U2AF2 and show at the global level that U2AF2 binds the maj...
ORGANISM(S): Homo sapiens 
Knockdown of ILF2/ILF3 (NF45/NF90) in the gastric cancer cell line SGC7901
We knocked down the expression of ILF2 in the A549 cell line and sequenced the RNA genes with the untreated A549 cells to find the regulatory gene of ILF2.
ORGANISM(S): Homo sapiens 
2019-06-06 | GSE126475 | GEO
Treatment of MM cells with non-targeting (NT) or ILF2 targeting oligonucleotide antisenses (ASOs)
Our data showed that lncRNA ELF3-AS1 could bind on the exon1 of ELF3-201 to form a double-stranded RNA molecule. This double-stranded RNA could interact with ILF2/ILF3 complex. To explore the biofunction of the interaction between ELF3-AS1 and ILF2/ILF3 complex, loss-of-function studies regarding IL...
ORGANISM(S): Homo sapiens 
2021-10-01 | GSE161544 | GEO
To understand the mechanistic basis of ILF2’s regulation of mRNA splicing in response to DNA damage in Multiple Myeloma, we performed RNA immunoprecipitation (RIP) and sequencing of ILF2-bound transcripts under both physiological and DNA damage (melphalan treatment) conditions. Cells were treated wi...
ORGANISM(S): Homo sapiens 
2017-05-23 | GSE83662 | GEO
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