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TranscriptomicsMicroRNA expression analysis of integrin-linked kinase gene silencing in A2780 cell line
Available evidence has suggested that integrin-linked kinase (ILK) underwent over-expression in ovarian cancer while specific gene silencing of ILK resulted in apoptosis of ovarian cancer cells. Here, potential mechanisms in which ILK induces cell apoptosis was explored from the perspective of micro...
ORGANISM(S): Homo sapiens 
2016-06-28 | E-GEOD-83721 | biostudies-arrayexpress
TranscriptomicsExpression data from Integrin-linked kinase (ILK)-deficient epidermis
ILK is essential for proper development of hair follicles, and for epidermal integrity and repair after injury. To better understand the pathways modulated by ILK in the epidermis, we compared the transcriptomes of ILK-deficient and -expressing epidermis using microarray analyses. Ilktm1Star (with f...
ORGANISM(S): Mus musculus 
2012-01-18 | E-GEOD-35129 | biostudies-arrayexpress
TranscriptomicsRole of ILK in cardiac regeneration
Two different mouse models of cardiac-specific ILK expression (ILKS343D and ILKR211A) were used to investigate the role of ILK in cardiac regeneration 4 groups with 3 mice (biological replicates) in each group with the total of 12 heart samples were used in this microarray experiment
ORGANISM(S): Mus musculus 
2012-12-25 | E-GEOD-25729 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of ILK-deficient hair follicle bulge stem cells
We sequenced mRNA from FACS purified hair follicle bulge stem cells from 21 d old control and ILK-deficient mice, 3 biological replicates each Examination of mRNA levels in control and ILK-deficient hair follicle bulge stem cells
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-68846 | biostudies-arrayexpress
TranscriptomicsActivation of ER-alpha network in MMTV-Wnt/ILK mammary tumors
A transgenic mouse model, MMTV-Wnt/ILK, with mammary specific expression of both Wnt-1 and ILK, was generated by crossing the two mouse lines MMTV-Wnt-1 and MMTV-ILK. Affymetrix Mouse Exon chips were hybridized with material from four independent mammary tumors from each MMTV-Wnt-1 and MMTV-Wnt/ILK ...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-19300 | biostudies-arrayexpress
TranscriptomicsDifferent exercise modalities have distinct effects on the transcriptome profile in the male rat femoral diaphysis
Mechanical loading is a key determinant of bone mass, geometry and strength and is essential to maintain optimal skeletal health. We hypothesized that spontaneous low-impact exercise would affect global gene transcript levels in cortical bone of growing rats. We used RNA-Seq to analyse the transcrip...
ORGANISM(S): Rattus norvegicus 
2015-11-02 | E-GEOD-67787 | biostudies-arrayexpress
ProteomicsCharacterisation of FAK- and ILK-dependent nuclear subproteomes
In addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, there is clear enrichment of proteins that localise to the nucleus, and conversely, we now report that nuclear prote...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-09 | PXD020179 | Pride
Cancer Ilk Adhesion Nucleus Human Fak 
ProteomicsRescue of disrupted mechanotransduction as a new therapeutic strategy in human dilated cardiomyopathy
Determine proteins interacting with ILK in transgenic mouse heart tissue.
ORGANISM(S): Mus musculus (Mouse) 
2014-06-26 | PXD001053 | Pride
Integrin-linked kinase 
ProteomicsProteomic Study to understand the role of ILK inhibitor in Meningioma cell line
This is a study to find the role of ILK inhibition in high grade Meningiomas.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-27 | MSV000092770 | MassIVE
GenomicsAn ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma.
An ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma.
PRJNA1002785 | ENA
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