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MetabolomicsImmune Stimulation via Wounding Alters Chemical Profiles of Adult Tribolium castaneum
Group-living individuals experience immense risk of disease transmission and parasite infection. In social and in some non-social insects, disease control with immunomodulation arises not only via individual immune defenses, but also via infochemicals such as contact cues and (defensive) volatiles t...
2023-04-24 | MTBLS2277 | MetaboLights
MetabolomicsCroquemort elicits activation of the immune deficiency pathway in ticks
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect arthropods remain e...
2023-04-27 | MTBLS686 | MetaboLights
MetabolomicsSerine Metabolism Tunes Immune Responses To Promote Oreochromis niloticus Survival upon Edwardsiella tarda Infection
Overactive immune response is a critical factor triggering host death upon bacterial infection. However, the mechanism behind the regulation of excessive immune responses is still largely unknown, and the corresponding control and preventive measures are also to be explored. In this study, we find t...
2021-08-18 | MTBLS2974 | MetaboLights
TranscriptomicsEffect of Drosophila immune proteins on gene expression in E. coli
Interaction between the host and invading pathogen determines the fate of both organisms during the infectious state. The host is equipped with a battery of immune reactions, while the pathogen displays a variety of mechanisms to compromise host immunity. Although bacteria alter their pattern of g...
ORGANISM(S): Escherichia coli 
2015-01-13 | E-GEOD-61604 | biostudies-arrayexpress
ModelsBianca2012 - Mathematical modeling of the immune system recognition to mammary carcinoma antigen
This model describes the humoral and cellular response of the immune system to a tumor associate antigen and the recognition process between B cells, T cells and antigen presenting cells. The model is used to analyze and investigate the competition between immune system cells and mammary carcinoma c...
2019-11-13 | MODEL1907260002 | BioModels
Immuno-oncology 
ProteomicsNATCANCER-A16341B 1 2 iNV GOV 3 4GOV
Oncolytic viruses (OVs) are replication-competent viruses that selectively infect tumor cells and induce anti-tumor responses. However, systemic delivery is limited by neutralizing antibodies and poor intratumoral bioavailability. We developed iNV-GOV, a tumor-targeted, low-immunogenic platform that...
ORGANISM(S): Homo sapiens (Human) 
2025-10-03 | PXD067837 | Pride
Inv gov and gov 
ModelsKareva2010 - Myeloid cells in tumour-immune interactions.
Myeloid cells in tumour-immune interactions. Kareva I1, Berezovskaya F, Castillo-Chavez C. Author information Abstract Despite highly developed specific immune responses, tumour cells often manage to escape recognition by the immune system, continuing to grow uncontrollably. Experimental work sugge...
2022-05-10 | MODEL2001310001 | BioModels
Immuno-oncology 
TranscriptomicsCircadian transcriptional profiling of peritoneal macrophages
In the immune system various parameters and immune functions are controlled by the circadian system. To investigate molecular mechanisms that link the circadian clock and the immune system we analyzed the transcriptom of peritoneal macrophages from mice collected in a time course for two consecutive...
ORGANISM(S): Mus musculus 
2010-11-24 | E-GEOD-25585 | biostudies-arrayexpress
TranscriptomicsC.elegans exposed to P. aeurigonsa: Colonized vs Non colonized animals
Transcriptional profiling of adult C.elegans exposed to E.coli or to GFP-expressing P. aeruginosa (strain PA14). For P. aeruginosa exposure, worms were separated into 2 groups - fully colonized (green) or non-colonized (dark). Three conditions (E.coli, P. aeurginosa colonized, and P. aeurginosa non-...
ORGANISM(S): Caenorhabditis elegans 
2012-07-19 | E-GEOD-39536 | biostudies-arrayexpress
TranscriptomicsComprehensive profiling of the early lung immune responses in the mouse model of tuberculosis
The lung host immune responses following M.tuberculosis infection in the mouse model of tuberculosis were assayed by studying the gene expression profiles at day 0, day 12, 15 and 21 post infection Mice were infected with M.tuberculosis via the aerosol route and the host gene induction during early ...
ORGANISM(S): Mus musculus 
2010-07-21 | E-GEOD-23014 | biostudies-arrayexpress
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