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Background: Acinetobacter baumannii is one of the most dangerous multidrug-resistant pathogens worldwide. Currently, 50-70% of clinical isolates of A. baumannii are extensively drug-resistant (XDR) and available antibiotic options against A. baumannii infections are limited. There are still needs to...
ORGANISM(S): Acinetobacter baumannii AYE Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 
2022-11-02 | PXD037507 | Pride
Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses
A primary Chlamydia trachomatis genital infection of Rhesus macaques identifies new immunodominant B-cell antigens
To identify immunodominant antigens that elicit a humoral immune response following a primary genital infection, rhesus monkeys were inoculated cervically with Chlamydia trachomatis serovar D. Serum samples were collected and probed with a protein microarray expressing 864/894 (96.4%) of the open re...
ORGANISM(S): Macaca mulatta Chlamydia trachomatis 
2020-05-27 | GSE151183 | GEO
Identification and characterization of a SARS-CoV-2 specific CD8 T cell response with immunodominant features
The COVID-19 pandemic caused by SARS-CoV-2 is a continuous challenge worldwide, and there is an urgent need to map the landscape of immunogenic and immunodominant epitopes recognized by CD8 T cells. Here, we analyze samples from 31 COVID-19 patients for CD8 T cell recognition of 500 peptide-HLA clas...
ORGANISM(S): Homo sapiens 
2021-03-25 | GSE169503 | GEO
An insulating myelin sheath ensures saltatory conduction of mechanosensory A afferents. Myelin damage results in the electrical instability of A fibers and the ability to generate pain in response to light touch/pressure (mechanical allodynia). We have hypothesized and then established that the re...
ORGANISM(S): Rattus norvegicus 
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