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ProteomicsIntegrating serum protein electrophoresis with mass spectrometry, a new workflow for M-protein detection and quantification
Serum protein electrophoresis (SPE) and immunofixation electrophoresis (IFE) are standard tools for multiple myeloma (MM) routine diagnostics. M-protein is a biomarker for MM that can be quantified with SPE and characterized with IFE. We have investigated combining SPE/IFE with targeted mass spectro...
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD016325 | Pride
Serum protein electrophoresis Immunofixation electrophoresis Targeted mass spectrometry Multiple myeloma M-protein 
UnknownDevelopment of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and middle-down de novo sequencing.
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S-EPMC8055720 | biostudies-literature
UnknownImmunotyping Provides Equivalent Results to Immunofixation in a Population with a High Prevalence of Monoclonal Gammopathies.
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S-EPMC8561783 | biostudies-literature
UnknownMass spectrometry vs immunofixation for treatment monitoring in multiple myeloma.
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S-EPMC9198943 | biostudies-literature
UnknownCOVID monoclonal antibody therapy detected by serum immunofixation electrophoresis.
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S-EPMC9352232 | biostudies-literature
UnknownA Comparison of gel (Hydragel 30) and capillary (Capillarys III Tera) electrophoresis for the characterization of human serum proteins.
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S-EPMC8145771 | biostudies-literature
UnknownAtypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma.
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S-EPMC3626496 | biostudies-literature
UnknownThe FLC dimer with lambda type may false-migrate to the position of "albumin" band by urine protein electrophoresis on Sebia agarose gel-based detection system.
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S-EPMC6818555 | biostudies-literature
UnknownDetection and Characterization of Paraproteinemia in Canine Chronic B-cell Lymphocytic Leukemia Using Routine and Free Light Chain Immunofixation.
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S-EPMC10087490 | biostudies-literature
UnknownComparison of serum free light chain and urine electrophoresis for the detection of the light chain component of monoclonal immunoglobulins in light chain and intact immunoglobulin multiple myeloma.
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S-EPMC4815727 | biostudies-literature
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