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TranscriptomicsTranscription profiling of Mycobacterium bovis with pYUB412 and pRD1-2F9 genes knocked-in to investigate the ESX-1 secretion system
The dedicated secretion system ESX-1 of Mycobacterium tuberculosis encoded by the extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10 kDa culture filtrate protein CFP-10, and is missing from the vaccine strains M.bovis BCG and M.microti. Here, we systematically ...
ORGANISM(S): Mycobacterium bovis 
2007-01-30 | E-BUGS-31 | biostudies-arrayexpress
UnknownEffect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial.
Not available
S-EPMC11514417 | biostudies-literature
GenomicsAn adjuvant strategy enabled by modulation of the physical properties of fungal ligands expands viral glycoprotein immunogenicity
An adjuvant strategy enabled by modulation of the physical properties of fungal ligands expands viral glycoprotein immunogenicity
PRJNA796058 | ENA
UnknownSTING-pathway modulation to enhance the immunogenicity of adenoviral-vectored vaccines.
Not available
S-EPMC9401198 | biostudies-literature
UnknownInterferon response and epigenetic modulation by <i>SMARCA4</i> mutations drive ovarian tumor immunogenicity.
Not available
S-EPMC11616711 | biostudies-literature
ProteomicsTarget profiling of organoplatinum(II) complex reveals role of protein tyrosine phosphatase 1B in modulating immunogenicity
Immunogenic cell death (ICD) inducers are valuable chemotherapeutic agents that elicit protective immune responses against tumors. However, the specific molecular targets directly associated with ICD remain less explored. Here, a Type II ICD inducer, Pt-ER, was validated as a bona fide ICD inducer w...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD065824 | Pride
Immunogenicity modulation Target identification Immunogenic cell death Chemoproteomics Protein tyrosine phosphatase 1b 
GenomicsHuman Volunteer Rotavirus Vaccine Study
Effect of antibiotic microbiome modulation on rotavirus vaccine immunogenicity: a human, randomized-control proof-of-concept trial
PRJEB25634 | ENA
UnknownEpigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Not available
S-EPMC9756225 | biostudies-literature
UnknownRetrovirus-Based Virus-Like Particle Immunogenicity and Its Modulation by Toll-Like Receptor Activation.
Not available
S-EPMC5640832 | biostudies-literature
UnknownAntigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.
Not available
S-EPMC6173722 | biostudies-literature
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