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GenomicsChIP-seq of neuroblastoma IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5 cell lines to identify TBX2, MYCN, H3K27ac, H3K4me1 and H3K4me3 binding sites
ChIP-seq to define bindings sites for TBX2, MYCN, H3K27ac, H3K4me1, H3K4me3 and Input in the cell lines IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5.
ORGANISM(S): Homo sapiens 
2018-10-16 | E-MTAB-6570 | biostudies-arrayexpress
GenomicsChIP-seq of neuroblastoma IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5 cell lines to identify TBX2, MYCN, H3K27ac, H3K4me1 and H3K4me3 binding sites
ChIP-seq of neuroblastoma IMR-32, CLB-GA, NGP, IMR-5/75, GI-M-EN, CHP-212, and IMR-5 cell lines to identify TBX2, MYCN, H3K27ac, H3K4me1 and H3K4me3 binding sites
PRJEB25363 | ENA
TranscriptomicsRNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls
RNA-seq upon JQ1 (1 uM), THZ1 (35 nM), UT (untreated) or combination treatment in the neuroblastoma cell line IMR-5/75. Analysis was performed 10h upon treament. Four biological replicates per condition.
ORGANISM(S): Homo sapiens 
2018-08-17 | E-MTAB-7025 | biostudies-arrayexpress
TranscriptomicsRNA-seq of IMR-5/75 neuroblastoma cell line upon TBX2 and/or MYCN knockdown
RNA-seq upon TBX2, MYCN or combination of TBX2 and MYCN knockdown in the neuroblastoma cell line IMR-5/75. Cells were transduced with two different shRNAs (shTBX2_2 and shTBX2_4) targeting TBX2 and a non-targeting control (NTC), and selected with puromycin. Cells were treated with doxycycline for sh...
ORGANISM(S): Homo sapiens 
2018-08-16 | E-MTAB-6568 | biostudies-arrayexpress
GenomicsRNA-seq of IMR-5/75 neuroblastoma cell line upon TBX2 and/or MYCN knockdown
RNA-seq of IMR-5/75 neuroblastoma cell line upon TBX2 and/or MYCN knockdown
PRJEB25334 | ENA
GenomicsRNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls
RNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls
PRJEB27831 | ENA
GenomicsNB IMR-5/75 medium perturbation
RNA seq data of human Neuroblastoma IMR-5/75 cell line grown under different medium conditions.
PRJEB25184 | ENA
TranscriptomicsTranscription profiling of human neuroblastoma cell line IMR-32 overexpressiong SQSTM1 and DPP3 to identify activators for the antioxidant response element
The antioxidant response element (ARE) is a cis-acting regulatory enhancer element found in the 5’ flanking region of many phase II detoxification enzymes. Upregulation of ARE-dependent target genes is known to have neuroprotective effects; yet, the mechanism of activation is largely unknown. By scr...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-6451 | biostudies-arrayexpress
GenomicsTargeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIP-seq IMR-5]
Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIP-seq IMR-5]
PRJNA603314 | ENA
TranscriptomicsNeuroblastoma cell lines treated with DAC (2'-deoxy-5-azacytidine), a DNA-methylation inhibitor
8 neuroblastoma (NB) cell lines (CLB-GA, IMR-32, SH-SY5Y, N206, CHP-902R, LAN-2, SK-N-AS, SJNB-1) were profiled on the Affymetrix HGU-133plus2,0 platform before and after treatment with DAC (2'-deoxy-5-azacytidine) to investigate the influence on expression after inhibiting DNA-methylation 8 NB cell...
ORGANISM(S): Homo sapiens 
2012-09-13 | E-GEOD-31229 | biostudies-arrayexpress
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