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Neutrophils are increasingly recognized as functionally versatile immune cells, with tissue-specific phenotypes that extend beyond their classical role in acute inflammation. In osteoarthritis (OA), neutrophils are abundant in synovial fluid (SF) which has been linked to worse symptoms., yet their p...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD073289 | Pride
Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis [Spatial Transcriptomics]
Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis [snRNA-seq]
Objective: To identify and characterize celltypes and distinct transcriptomic signatures present in the infrapatellar fat pad (IFP) of knee OA patients using single-nucleus RNA sequencing.
ORGANISM(S): Homo sapiens 
2024-10-07 | GSE253198 | GEO
Objective: To spatially resolve the identified celltypes, subtypes and transcriptomic profiles from single-nuclei RNA-seq with matched 12 infrapatellar fat pad of knee OA patients using spatial transcriptomics sequencing.
ORGANISM(S): Homo sapiens 
2024-10-07 | GSE253199 | GEO
Single-cell atlas of human infrapatellar fat pad and synovium unravels mechanisms of osteoarthritis-induced joint pathology
Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis
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