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MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
TranscriptomicsBiological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols
We compared early biological changes in mice after inhalation exposures to cigarette smoke or e-vapor aerosols (MarkTen® cartridge with Carrier, Test-1, or Test-2 formulations; 4% nicotine). Female C57BL/6 mice were exposed to 3R4F cigarette smoke or e-vapor aerosols by nose-only inhalation for up t...
ORGANISM(S): Mus musculus 
2021-02-28 | E-MTAB-10166 | biostudies-arrayexpress
TranscriptomicsExpression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (ER and DR)
To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge between early responders (ERs) and dual responders (DRs) following allergen inhalation challenge Blood was collected immediately prior to, and two hours after challenge The...
ORGANISM(S): Homo sapiens 
2013-09-20 | E-GEOD-40240 | biostudies-arrayexpress
TranscriptomicsEpigenetics effects of formaldehyde inhalation exposure
We set out to test the hypothesis that formaldehyde inhalation exposure significantly alters miRNA expression profiles within the nasal epithelium of nonhuman primates. Here, cynomolgus macaques were exposed to 0, 2, and 6 ppm formaldehyde for 6 hours/day across two consecutive days. RNA was extract...
ORGANISM(S): Macaca fascicularis 
2012-09-01 | E-GEOD-34978 | biostudies-arrayexpress
UnknownAutomated crude oil vapor inhalation exposure system.
Not available
S-EPMC9876599 | biostudies-literature
UnknownAcute inhalation of combustion smoke triggers neuroinflammation and persistent anxiety-like behavior in the mouse.
Not available
S-EPMC6003701 | biostudies-literature
MetabolomicsAn LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

INTRODUCTION: Noise-induced hearing loss (NIHL) is an increasing problem in society and accounts for a third of all cases of acquired hearing loss. NIHL is caused by formation of reactive oxygen species (ROS) in the cochlea causing oxidative stress. Hydrogen gas (H2) ...

2021-10-06 | MTBLS2418 | MetaboLights
UnknownModeling vascular inflammation and atherogenicity after inhalation of ambient levels of ozone: exploratory lessons from transcriptomics.
Not available
S-EPMC7456636 | biostudies-literature
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells from healthy volunteers exposed to diesel exhaust inhalation
Background: Diesel exhaust (DE) is the primary source of urban fine particulate matter, which has been associated with cardiovascular disease in epidemiological studies. These effects may be related to oxidative stress and systemic inflammation with resulting perturbation of vascular homeostasis. Pe...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7462 | biostudies-arrayexpress
UnknownDevelopment of a large-scale computer-controlled ozone inhalation exposure system for rodents.
Not available
S-EPMC7055063 | biostudies-literature
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