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ProteomicsComputational prediction combined with proteogenomics unveils widespread non-AUG translation initiation events in plants
Non-AUG translation initiation is crucial for regulating translation, which can generate N-terminally extended protein isoforms with diverse biological functions. However, a comprehensive view of non-AUG translation initiation events with N-terminal extensions (NTEs) across monocots and dicots remai...
ORGANISM(S): Glycine max Zea mays (Maize) Oryza sativa (Rice) 
2026-04-27 | PXD058528 | Pride
Non-aug translation initiation  n-terminally extended protein isoforms  n-terminal extensions (ntes)  upstream translation initiation sites (utiss)  proteogenomics  monocots and dicots 
ModelsSeptation Initiation Network
The Septation Initiation Network (SIN) controls cytokinesis in fission yeast. This model uses CDK activity levels as control nodes to simutate SIN related events throughout different stages of the cell cycle. This model was optimized using single knock-out experiments and has made in silico predicti...
4705 | Cell Collective
TranscriptomicsReplication initiation sites in cancer cells
Reads from massively parallel sequencing of RNA primed, short nascent strands from asynchronously growing cancer cells (K562, MCF7). Newly replicated DNA was isolated based on size (400-800 bp) and the presence of a short RNA stretch at the 5' end using lambda exonuclease. Purified nascent strands w...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-28911 | biostudies-arrayexpress
TranscriptomicsRNA-seq GLV6 overexpression during lateral root initiation in Arabidopsis thaliana
The goal of this experiment was to identify the downstream targets of the GOLVEN6 peptide signaling pathway in Arabidopsis thaliana, specifically during lateral root initiation. Using an estradiol inducible GLV6 overexpression construct in wildtype and rgi1rgi5 double mutant (mutant in receptors for...
ORGANISM(S): Arabidopsis thaliana 
2022-02-13 | E-MTAB-10891 | biostudies-arrayexpress
ModelsRay2013 - Meiotic initiation in S. cerevisiae
Ray2013 - Meiotic initiation in S. cerevisiae A mathematical representation of early meiotic events, particularly feedback mechanisms at the system level and phosphorylation of signalling molecules for regulating protein activities, is described here Th...
2024-09-02 | BIOMD0000000626 | BioModels
TranscriptomicsWaves of early transcriptional activation and pluripotency program initiation along human preimplantation development.
The events regulating human preimplantation development are still largely unknown, due to scarcity of material, ethical and legal limitations, and lack of reliable techniques to faithfully amplify the transcriptome of a single cell. Nonetheless, knowledge in human embryology is gathering renewed int...
ORGANISM(S): Homo sapiens 
2011-07-18 | E-GEOD-29397 | biostudies-arrayexpress
GenomicsAbiotic stress-response reprogramming events underlie successful initiation of apomixis
Abiotic stress-response reprogramming events underlie successful initiation of apomixis
PRJEB14921 | ENA
TranscriptomicsThe landscape of RNA polymerase II transcription initiation in C. elegans reveals a novel regulatory architecture
It has recently been shown that RNA Polymerase II transcription is far more extensive than previously thought, much of it not associated with protein-coding genes. To investigate this phenomenon, we determined the genome-wide landscape of RNA Polymerase II transcription initiation and elongation in...
ORGANISM(S): Caenorhabditis elegans 
2013-03-29 | E-GEOD-42819 | biostudies-arrayexpress
GenomicsMost human DNA replication initiation is dispersed throughout the genome with only a minority within previously identified initiation zones
Most human DNA replication initiation is dispersed throughout the genome with only a minority within previously identified initiation zones
PRJNA1105043 | ENA
TranscriptomicsSequencing the cap-snatching repertoire of H1N1 influenza provides insight into the mechanism of viral transcription initiation
The influenza polymerase cleaves host RNAs ~10–13 nucleotides downstream of their 5′ ends and uses this capped fragment to prime viral mRNA synthesis. To better understand this process of cap snatching, we used high-throughput sequencing to determine the 5′ ends of A/WSN/33 (H1N1) influenza mRNAs. T...
ORGANISM(S): Influenza A virus (A/WSN/1933(H1N1)) 
2015-04-23 | E-GEOD-65101 | biostudies-arrayexpress
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