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TranscriptomicsInducible repositioning of mouse gene tethering to the inner nuclear membrane
Nuclear compartmentalization appears to play an important role in regulating metazoan genes. While studies on immunoglobulin (Ig) and other loci have correlated positioning at the nuclear lamina with gene repression, the functional consequences of this compartmentalization remain untested. We devise...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10176 | biostudies-arrayexpress
ProteomicsLEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
Quantitative crosslinking analysis to probe in vitro conformational dynamics governing ESCRT-mediated nuclear envelope formation. CHMP7 was crosslinked with D12-BS3 while CHMP7 in the presence of LEM2 winged helix domain was crosslinked with H12-BS3. Samples were mixed after crosslinking and analy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-24 | MSV000084837 | MassIVE
TranscriptomicsTranscription profiling of C2C12 cells cultured either in 20% serum (undifferentiated) or in 2% horse serum (differentiated) to detail the global changes of gene expression in lamins and nuclear envelope assoicated proteins during myogenesis
During muscle differentiation, myogenesis sepcific genes are differentially regulated, including Lamins that function at least in maintenance of nuclear architecture and regulation of gene expression. We used microarrays to detail the global changes of gene expression in lamins and nuclear envelope ...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4694 | biostudies-arrayexpress
GenomicsInner-envelope phosphatidylethanolamine promotes DNA replication and nucleoid- biogenesis in early chloroplast development
Inner-envelope phosphatidylethanolamine promotes DNA replication and nucleoid- biogenesis in early chloroplast development
PRJNA1124885 | ENA
ProteomicsLipid Metabolism and Contact Site Homologs Are Enriched at the Chloroplast Envelope-Thylakoid Interface
Biogenesis and maintenance of the photosynthetic thylakoid membrane requires transport of lipids from their site of synthesis in the chloroplast envelopes to their destination in the thylakoid. While vesicle trafficking is likely involved, we hypothesized a complementary mechanism involving direct m...
ORGANISM(S): Pisum sativum (Garden pea) 
2026-04-29 | PXD065686 | Pride
Lightthy Heavy inner envelope Light thylakoid Heavyie Thylakoid Inner envelope 
TranscriptomicsRequirement for Sun1 in the expression of meiotic reproductive genes and piRNA
The inner nuclear envelope (NE) proteins interact with the nuclear lamina and participate in the architectural compartmentalization of chromosomes. The association of NE proteins with DNA contributes to the spatial rearrangement of chromosomes and their gene expression. Sun1 is an inner nuclear memb...
ORGANISM(S): Mus musculus 
2009-03-11 | E-GEOD-12867 | biostudies-arrayexpress
OtherInner-envelope phosphatidylethanolamine promotes DNA replication and nucleoid- biogenesis in early chloroplast development
Proplastid-to-chloroplast transitconversion during early plant development involves exintensive genome replication and nucleoid structurale changes of the nucleoid during plant early development. In addition, and the nucleoid distribution shifts from ring-shaped assemblies near the inner- envelope t...
ORGANISM(S): Arabidopsis thaliana 
2026-05-22 | GSE270028 | GEO
ProteomicsCombining proximity labeling and crosslinking mass spectrometry for proteomic dissection of nuclear envelope interactome
Analysis of LAP1 interactome in HEK293T cells using proximity labeling or proximity labeling combined with crosslinking methods.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-20 | MSV000084606 | MassIVE
ProteomicsProteomics analysis of nuclear envelope, cytoplasmic membrane and nuclear contents fractions isolated from mesenchymal stem cells, adipocytes and myocytes
We used shotgun proteomics to analyze three subcellular fractions isolated from mesenchymal stem cells and from differentiated adipocytes and myocytes: nuclear envelopes (NEs), cytoplasmic membranes and nuclear contents. The proteomics data were analyzed by a NSAF-based scoring system to calculate...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-11-27 | MSV000083166 | MassIVE
UnknownAssociation between LCE gene polymorphisms and psoriasis vulgaris among Mongolians from Inner Mongolia.
Not available
S-EPMC5915497 | biostudies-literature
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