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UnknownComparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing.
Not available
S-EPMC4531509 | biostudies-literature
TranscriptomicsGenomic profiling of primary and metastatic clear cell renal cell carcinoma by array-based comparative genomic hybridization.
In this study, we investigated CNAs of 20 primary clear cell renal cell caricinomas (ccRCCs), 20 corresponding metastases and another subsets of 30 primary ccRCCs by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 primary ccRCCs, 20 corresponding metastases and anot...
ORGANISM(S): Homo sapiens 
2014-10-16 | E-GEOD-43477 | biostudies-arrayexpress
ProteomicsInternally Tagged Ubiquitin: a Tool to Identify Linear Polyubiquitin-modified Proteins by Mass Spectrometry
Even though ubiquitination controls a plethora of cellular processes, modifications by linear polyubiquitin have so far only been linked with acquired and innate immunity, lymphocyte development and genotoxic stress response. Until now, a single E3 ligase complex (LUBAC), one specific deubiquitinase...
ORGANISM(S): Homo sapiens (Human) 
2017-03-21 | PXD005878 | Pride
Ubiquitin Proteomics Human Pull-down 
TranscriptomicsIdentification of a novel NF-kB target gene in human triple-negative breast cancer cells
Analysis of human triple-negative breast cancer cells (TNBCs) which have high NF-kB activity. Proteins derived from NF-κB target genes might be molecular targets for cancer therapy. Results provide new insights into tumor proliferation mechanisms. Exp. 1: Mock MDA-MB-436 cells vs. MDA-MB-436 cells ...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-56812 | biostudies-arrayexpress
UnknownLethal co-expression intolerance underlies the mutually exclusive expression of ASCL1 and NEUROD1 in SCLC cells.
Not available
S-EPMC11906894 | biostudies-literature
ProteomicsTMT-based quantitative proteomic analysis of SAHA-treated human HeLa cells
We performed a TMT-based quantitative proteomic analysis of SAHA-perturbed human HeLa cells using advanced RTS platform on Orbitrap Eclipse Tribrid MS system.
ORGANISM(S): Homo Sapiens (human) 
2023-06-09 | PXD038681 | JPOST Repository
TranscriptomicsLoss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor/TRAF6 signaling
TRAF-interacting protein with forkhead-associated domain B (TIFAB) is a haploinsufficient gene in del(5q) Myelodysplastic syndrome (MDS). Hematopoietic-specific deletion of Tifab results in progressive bone marrow (BM) and blood defects, including skewed hematopoietic stem/progenitor cells (HSPC) pr...
ORGANISM(S): Mus musculus 
2015-09-12 | E-GEOD-72936 | biostudies-arrayexpress
ProteomicsProteomic identification of PTMs of MAVS 1-200
To identify PTMs of MAVS, we overexpressed His-Flag-tagged hMAVS 1-200 in 293T cells and cell lysates were analyzed by LC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2025-07-23 | PXD061814 | JPOST Repository
ProteomicsProteomic identification of PTMs of MAVS 1-200
To identify PTMs of MAVS, we overexpressed His-Flag-tagged hMAVS 1-200 in 293T cells and cell lysates were analyzed by LC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2025-07-23 | PXD058405 | JPOST Repository
ProteomicsProteomic identification of MAVS carboxylation site–associated proteins
To identify proteins that differentially interact with carboxylated and non-carboxylated MAVS, we overexpressed Flag-tagged WT or 4A mutant (D53A, E70A, E80A, and D83A) forms of hMAVS in 293T cells and analyzed the interactors using immunoprecipitation followed by mass spectrometry (MS). Cell lysate...
ORGANISM(S): Homo Sapiens (human) 
2025-07-23 | PXD058403 | JPOST Repository
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