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ProteomicsMicroplitis mediator venom protein LC-MSMS
Insects mount an innate immune response to defend against the foreign invading microorganisms and parasites. To be successful parasites, endoparasitoid wasps need to be able to suppress the immune responses of their hosts. This allows the wasp eggs to hatch and the larvae to develop inside the host....
ORGANISM(S): Microplitis mediator 
2019-01-07 | PXD007905 | Pride
Lc-msms Venom Micrioplitis mediator 
ProteomicsIntraspecific Venom Variation between Tetrastichum brontispae strains
The venom apparatus is a conserved organ in parasitoid wasps that shows adaptations correlated with life-style diversification. Recent venom analyses from selected species reveal considerable complexity and high diversity in venom composition existing not only between closely related species but eve...
ORGANISM(S): Tetrastichus 
2018-11-06 | PXD004653 | Pride
Tetrastichus brontispae Venom Lable-free 
ProteomicsToxins from scratch? - Diverse, multimodal gene origins in the predatory robber fly Dasypogon diadema indicate dynamic venom evolution in dipteran insects
Venoms and the toxins they contain represent molecular adaptations that have evolved on numerous occasions throughout the animal kingdom. However, the processes that shape venom protein evolution are poorly understood because of the scarcity of whole genome data available for comparative analyses of...
ORGANISM(S): Dasypogon diadema 
2019-06-13 | PXD013358 | Pride
Toxin Venom Dasypogon Robber fly 
ProteomicsVenom evolution of 15 neotropical ants
To comprehend the drivers underlying venom variation in ants, we selected 15 Neotropical species and recorded a range of traits, including ecology, morphology, and venom bioactivity. Principal component analysis of both morphological and venom bioactivity traits revealed that stinging ants display t...
ORGANISM(S): Pachycondyla commutata Neoponera goeldii Anochetus emarginatus Pseudomyrmex termitarius Odontomachus haematodus Pseudomyrmex viduus Pseudomyrmex penetrator Odontomachus hastatus Odontomachus scalptus Daceton armigerum Neoponera apicalis Odontomachus mayi Neoponera inversa Pseudomyrmex gracilis 
2024-10-16 | PXD050348 | Pride
Transcriptome Ant Venom Lc-ms/ms 
ProteomicsAssassin bug (Pristhesancus plagipennis) venom proteome
Assassin bugs (Hemiptera: Heteroptera: Reduviidae) are venomous insects that prey on invertebrates. Assassin bug venom has features in common with venoms from other animals, such as paralysing and lethal activity when injected, and a molecular composition that includes disulfide-rich peptide neuroto...
ORGANISM(S): Pristhesancus sp. 00004635 
2017-11-14 | PXD004804 | Pride
Venom Reduviidae Assassin bug Heteroptera 
TranscriptomicsMultiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study
Allergen-specific immunotherapy (AIT) induces immune tolerance, showing the highest success rate (>95%) for insect venom while a much lower chance for pollen allergy. However, the molecular switches leading to successful durable tolerance restoration remain elusive. Here we applied a multilayer-omic...
ORGANISM(S): Homo sapiens 
2024-10-30 | GSE240503 | GEO
ProteomicsConvergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Gene duplication, accompanied by modification of the expression and/or function of one of the duplicates under the action of positive selection, followed by further duplication to produce multigene families of toxins is a well-documented process in venomous animals. This evolutionary model has been ...
ORGANISM(S): Leptopilina boulardi Leptopilina heterotoma 
2023-06-09 | PXD041695 | Pride
Gene duplication Venom Evolution Positive selection Parasitoids Rhogap Ovarian calyx 
ProteomicsDivergent venom effectors correlate with ecological niche in neuropteran predators
Neuropteran larvae are fierce predators that use venom to feed on arthropods, but their venom system is poorly understood. The iconic antlions (Myrmeleontidae) are adapted to dry, sandy habitats, where they use pitfall traps and venom to catch and subdue large arthropod prey. The aphid lions, larvae...
ORGANISM(S): Euroleon nostras Chrysoperla carnea 
2024-08-13 | PXD047026 | Pride
Antlions Venom Aphid lions Euroleon nostras Comparative venomics Chrysoperla carnea 
ProteomicsReduviid venom composition to inform venom evolution and evolution of blood-feeding
We found that assassin bugs from the earliest-diverging subfamily of higher Reduviidae (Peiratinae), as well as a subfamily closely related to Triatominae (Stenopodainae) have venom that is highly similar in composition to that produced by previously examined reduviids from Harpactorinae and Reduvii...
ORGANISM(S): Oncocephalus Ectomocoris 
2024-07-30 | PXD050854 | Pride
Reduviidae  venom  molecular evolution  anticoagulant 
ProteomicsTrichopria drosophilae venom, LC-MS/MS-based proteomics
Identification of venom proteins of Drosophila parasitoid, Trichopria drosophilae.
ORGANISM(S): Trichopria drosophilae 
2024-06-20 | PXD038251 | Pride
Trichopria drosophilae Venom Lc-ms/ms 
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