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UnknownCompetition of individual domain folding with inter-domain interaction in WW domain engineered repeat proteins.
Not available
S-EPMC7299559 | biostudies-literature
UnknownA unified approach to protein domain parsing with inter-residue distance matrix.
Not available
S-EPMC9919455 | biostudies-literature
ProteomicsMapping the protein-protein interaction interface between recombinant CB1R and GlyT2 using cross-linking mass spectrometry
This project aims to elucidate a novel molecular mechanism driving mechanical allodynia, a debilitating neuropathic pain condition. We focus on a spinal cord “allodynia gate” circuit in which nerve injury leads to disinhibition of protein kinase Cγ (PKCγ) excitatory neurons. Our findings reveal that...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD070478 | Pride
Cb1r protein Cx-ms Glyt2 protein 
ProteomicsAltered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross‐Linking, MS/MS, and NMR
The endogenous cellular prion protein (PrPC) can misfold into the scrapie isoform (PrPSc) and cause fatal infectious diseases. Despite significant research on the prion protein, both its normal function and whether alterations to that function play a critical role in prion diseases remain unknown. T...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-16 | PXD012427 | Pride
Cross-linking Inter-domain protein interaction Mass spectrometry Prion 
UnknownThe four hydrophobic residues on the Hsp70 inter-domain linker have two distinct roles.
Not available
S-EPMC5737734 | biostudies-literature
UnknownDnaA protein DNA-binding domain binds to Hda protein to promote inter-AAA+ domain interaction involved in regulatory inactivation of DnaA.
Not available
S-EPMC3190739 | biostudies-literature
TranscriptomicsGlobal changes in the nuclear positioning of chromatin domains and genomic interactions that orchestrate B cell fate
The genome is folded into domains that are located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with i...
ORGANISM(S): Mus musculus 
2012-10-09 | E-GEOD-40173 | biostudies-arrayexpress
UnknownNLRP7 inter-domain interactions: the NACHT-associated domain is the physical mediator for oligomeric assembly.
Not available
S-EPMC4172174 | biostudies-literature
UnknownDynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles.
Not available
S-EPMC5289058 | biostudies-literature
UnknownDomain-domain interactions underlying herpesvirus-human protein-protein interaction networks.
Not available
S-EPMC3131297 | biostudies-literature
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