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Progesterone receptor (PR) isoforms, PRA and PRB, both progesterone-independent and dependent modulated the biology of breast cancer cells. The different phenotypes in breast cancer mediated by PRA and PRB could due to the differences of their structures, leading to the distinct protein interacting ...
ORGANISM(S): Homo sapiens (Human) 
2021-03-08 | PXD023920 | Pride
Heat shock protein 90 (HSP90) is a highly abundant molecular chaperone that interacts with many other intracellular proteins to regulate various cellular processes. However, compositions of the HSP90-interacting complex remain underinvestigated. This study thus aimed to characterize such complex in ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-17 | PXD011432 | Pride
TEAD switches interacting partners along neural progenitor lineage progression to execute distinct functions
A testis specific antigen, TSA70 was identified in the lab which was homolgous to the sperm tail outer dense fiber protein (ODF2). ODFs are disulphide stabilised during epididymal maturation and are required for sperm motility. ODF2 is reported to bind macrophage migration inhibitory factor (MIF), a...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-01-23 | PXD002296 | Pride
NSD2 is a histone methyltransferase that specifically dimethylates histone H3 lysine 36 (H3K36me2), a modification associated with gene activation. Dramatic overexpression of NSD2 in t(4;14) multiple myeloma (MM) and an activating mutation of NSD2 discovered in acute lymphoblastic leukemia (ALL) are...
ORGANISM(S): Homo sapiens (Human) 
2019-06-27 | PXD013759 | Pride
Eomesodermin (Eomes) interacting partners via RIME in mouse trophoblast stem cells
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-05-14 | MSV000097887 | MassIVE
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