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MetabolomicsLimited vertical transmission but profound immune dysregulation at the maternal-fetal interface after SARS-CoV-2 infection

The endemic of SARS-CoV-2 underscores the imperative to elucidate its effects on pregnancy, particularly regarding the potential for vertical transmission and its influence on the early maternal-fetal interface, which remain insufficiently defined. To address this, we performed an extensive cohor...

2026-03-05 | MTBLS13103 | MetaboLights
ProteomicsIntercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells.
bacterial amyloidosis, prion-like, RepA-WH1, intercellular transmission,proteotoxic cross-aggregation
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-05-26 | PXD018245 | Pride
Bacterial amyloidosis Repa-wh1 Prion-like Intercellular transmission Proteotoxic cross-aggregation 
TranscriptomicsCell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression.
Intracellular microbes have evolved efficient strategies for transitioning from one cell to another in a process termed intercellular transmission. Here we show that host cell transmission of the obligate intracellular parasite Toxoplasma gondii is closely tied to specific cell cycle distributions, ...
ORGANISM(S): Toxoplasma gondii 
2010-12-27 | E-GEOD-20480 | biostudies-arrayexpress
GenomicsIntercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency
Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency
PRJNA735518 | ENA
ProteomicsMigrions, a Migrasome-mediated unit for Intercellular Viral Transmission
Efficient intercellular virus spread significantly contributes to overall pathogenesis and virulence. Our study reveals that viral RNAs and proteins are transported to migrasomes during cell migration. This chimera of migrasomes and virions, termed Migrion, demonstrates infectivity, resulting in gre...
ORGANISM(S): Mus Musculus 
PXD056270 |
UnknownArc mediates intercellular tau transmission via extracellular vesicles.
Not available
S-EPMC11526995 | biostudies-literature
TranscriptomicsIntercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency
Intercellular transmission of the second messenger 2′,3′‐cGAMP, synthesized by the viral DNA sensor cGAMP synthase (cGAS), is a potent mode of bystander activation during host defense. However, whether this mechanism also contributes to cGAS-dependent autoimmunity remains unknown. Here, using a muri...
ORGANISM(S): Mus musculus 
2021-07-09 | GSE176225 | GEO
UnknownIntercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism.
Not available
S-EPMC7858244 | biostudies-literature
UnknownExosomes Mediate Intercellular Transmission of Porcine Reproductive and Respiratory Syndrome Virus.
Not available
S-EPMC5790938 | biostudies-literature
TranscriptomicsCell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression.
Intracellular microbes have evolved efficient strategies for transitioning from one cell to another in a process termed intercellular transmission. Here we show that host cell transmission of the obligate intracellular parasite Toxoplasma gondii is closely tied to specific cell cycle distributions, ...
ORGANISM(S): Toxoplasma gondii 
2010-12-27 | GSE20480 | GEO
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