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UnknownTranscriptional dysregulation of Interferome in experimental and human Multiple Sclerosis.
Not available
S-EPMC5566335 | biostudies-literature
UnknownInterferome signature dynamics during the anti-dengue immune response: a systems biology characterization.
Not available
S-EPMC10449254 | biostudies-literature
UnknownIntegrative immunology identified interferome signatures in uveitis and systemic disease-associated uveitis.
Not available
S-EPMC12014655 | biostudies-literature
ProteomicsDeciphering of the human interferome and its kinetics of protein induction and repression by mass spectrometry-based quantitative proteome analysis
Interferons (IFNs) are pleotropic cytokines secreted upon encounter of pathogens and tumors. Applying their antipathogenic, antiproliferative and immune stimulatory capacities, recombinant IFNs are frequently prescribed as drugs to treat different diseases. IFNs act by changing the transcription of ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-25 | PXD006442 | Pride
Interferome Interferon gamma Label-free quantification Interferon alpha 
UnknownThe antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.
Not available
S-EPMC8423302 | biostudies-literature
UnknownCFTR modulators partially restore the epithelial interferome in Aspergillus infection to improve clinical outcome.
Not available
S-EPMC12878693 | biostudies-literature
Genomics
The antiviral state has shaped the composition of the vertebrate interferome (RNA-Seq dataset2)
PRJEB39825 | ENA
Genomics
The ‘antiviral state’ has shaped the CpG composition of the vertebrate interferome
PRJEB29677 | ENA
TranscriptomicsENHANCED INTERFERON-SENSING BY AGGRESSIVE CHRONIC LYMPHOCYTIC LEUKEMIA CELLS
Purpose: to determine the CLL-B cells' interferome Methods: CLL cells from 3 of the patients previously classified as responders were purified and treated with anifrolumab in vitro and RNA was analyzed by RNAseq. 
ORGANISM(S): Homo sapiens 
2022-02-18 | GSE196741 | GEO
TranscriptomicsType I interferome in human gut CD4 T cells
Rationale: Humans encode 12 different IFNa proteins. All of them, except IFNa1 (only binds with IFNAR1), bind with IFNAR1 and IFNAR2 to activate their downstream functions. Currently in the field, it is still a debate whether there are qualitative difference between different IFNa subtypes or the di...
ORGANISM(S): Homo sapiens 
2020-10-02 | GSE156844 | GEO
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