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ORGANISM(S): Mus musculus 

Maternal folic acid intake is crucial for the development of the offspring's nervous system, and folic acid metabolism disorders during pregnancy lead to neural tube defects (NTDs) in the fetus. Folic acid and vitamins biosynthesis is a major biochemical feature of gut microbiota. The complex and...

2022-12-05 | MTBLS4893 | MetaboLights

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-12-05 | MTBLS4894 | MetaboLights
Living organisms adjust their proteome in response to nutritional conditions, but how these changes are transmitted across generations remains unclear. While unicellular organisms can inherit proteome states through symmetric division, multicellular organisms face limitations due to the soma-germlin...
ORGANISM(S): Caenorhabditis elegans 
2026-02-10 | PXD060999 | Pride
Intergenerational metabolic priming by sperm piRNAs
Epigenetic signatures of intergenerational exposure to violence during pregnancy
Intergenerational genomic DNA methylation patterns in mouse hybrid strains Reduced representation bisulfite sequencing from mouse liver, using MspI restriction enzyme, and selecting ~100-300bp size fraction.
ORGANISM(S): Mus musculus 
Intergenerational hormesis is regulated by heritable 18S rRNA methylation 18S rRNA methylation is heritably transmitted to regulate intergenerational hormesis
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